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Gene Review

AEP1  -  Aep1p

Saccharomyces cerevisiae S288c

Synonyms: ATPase expression protein 1, mitochondrial, NCA1, Nuclear control of ATPase messenger RNA expression protein 1, YM9916.03, YMR064W
 
 
 
 
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High impact information on AEP1

  • Characterization of a second nuclear gene, AEP1, required for expression of the mitochondrial OLI1 gene in Saccharomyces cerevisiae [1].
  • This fragment encoded five open reading frames: the longest of these, at 1,554 nucleotides, was identified as the AEP1 gene, since disruption of this reading frame generated a non-conditional pet strain unable to synthesize subunit 9 [1].
  • Hybridization studies with AEP1-specific probes indicate that the gene is located on chromosome XIII and produces several poly(A)+ transcripts ranging in size from 0.9 to 2.7 kb [1].
  • In this study the AEP1 gene has been cloned from a wild-type yeast genomic library by genetic complementation of a temperature-conditional aep1 strain at the restrictive temperature [1].

References

 
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