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Gene Review: 

MSS11  -  Mss11p

Saccharomyces cerevisiae S288c

Synonyms: Multicopy suppressor of STA genes protein 11, Transcription activator MSS11, YM8520.13C, YMR164C
 
 
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High impact information on MSS11

  • Both MSN1 and MSS11 are involved in the co-regulation of starch degradation and invasive growth [1].
  • The deletion of MSS11 leads to a non-flocculent phenotype, and specific domains of Mss11p that are critical for the induction of flocculation are identified [2].
  • Moreover, the STA10 repression is suppressed completely or partially by the introduction of a single copy of the FLO8 or MSS11 genes [3].
  • A strain transformed with multiple copies of MSS11 exhibits increased levels of STA2 mRNA and, consequently, increased glucoamylase activity [4].
  • Deletion of MSS11, located on chromosome XIII, results in media-dependent absence of glucoamylase synthesis [4].

References

  1. Msn1p/Mss10p, Mss11p and Muc1p/Flo11p are part of a signal transduction pathway downstream of Mep2p regulating invasive growth and pseudohyphal differentiation in Saccharomyces cerevisiae. Gagiano, M., van Dyk, D., Bauer, F.F., Lambrechts, M.G., Pretorius, I.S. Mol. Microbiol. (1999) [Pubmed]
  2. The regulation of Saccharomyces cerevisiae FLO gene expression and Ca2+ -dependent flocculation by Flo8p and Mss11p. Bester, M.C., Pretorius, I.S., Bauer, F.F. Curr. Genet. (2006) [Pubmed]
  3. STA10 repression of STA gene expression is caused by a defective activator, flo8, in Saccharomyces cerevisiae. Kim, T.S., Ahn, J.Y., Yoon, J.H., Kang, H.S. Curr. Genet. (2003) [Pubmed]
  4. MSS11, a novel yeast gene involved in the regulation of starch metabolism. Webber, A.L., Lambrechts, M.G., Pretorius, I.S. Curr. Genet. (1997) [Pubmed]
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