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Gene Review

ALD2  -  aldehyde dehydrogenase (NAD(+)) ALD2

Saccharomyces cerevisiae S288c

Synonyms: ALD5, YM8520.19C, YMR170C
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Disease relevance of ALD2


High impact information on ALD2


Biological context of ALD2

  • We characterize here the tandem-repeated ORFs YMR170c and YMR169c as the cytoplasmic stress-inducible isoforms, with gene names ALD2 and ALD3, respectively [4].

Associations of ALD2 with chemical compounds

  • ALD2 is only induced by osmotic stress and glucose exhaustion [4].
  • A proposal for nomenclature of aldehyde dehydrogenases in Saccharomyces cerevisiae and characterization of the stress-inducible ALD2 and ALD3 genes [4].

Regulatory relationships of ALD2

  • Using quantitative PCR analysis, ALD6 was found to be the most highly expressed among the ALD2 to ALD6 genes [5].

Other interactions of ALD2

  • Although no significant differences in the transcriptional levels of ALD2 to ALD6 encoding acetaldehyde dehydrogenase (ALD) between 2DGR19 and NCYC1245 were observed, ALD activity in 2DGR19 was lower [5].


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