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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

PPE1  -  carboxylesterase-mitochondrial 37S...

Saccharomyces cerevisiae S288c

Synonyms: PME-1, Protein phosphatase methylesterase 1, YHR075C, Yms2
 
 
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High impact information on PPE1

  • Inactivation of PPM1 or overexpression of PPE1, the yeast gene homologous to bovine methylesterase, yields phenotypes similar to those observed after inactivation of either regulatory subunit [1].
  • Thus, unlike HXT11 and PPE1, SIK1 over-expression is also associated with mitotic functions [2].

References

  1. Carboxyl methylation of the phosphoprotein phosphatase 2A catalytic subunit promotes its functional association with regulatory subunits in vivo. Wu, J., Tolstykh, T., Lee, J., Boyd, K., Stock, J.B., Broach, J.R. EMBO J. (2000) [Pubmed]
  2. A new enrichment approach identifies genes that alter cell cycle progression in Saccharomyces cerevisiae. Bogomolnaya, L.M., Pathak, R., Cham, R., Guo, J., Surovtseva, Y.V., Jaeckel, L., Polymenis, M. Curr. Genet. (2004) [Pubmed]
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