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Gene Review

MAK10  -  Mak10p

Saccharomyces cerevisiae S288c

Synonyms: Glucose repressible protein MAK10, L-A virus GAG protein N-acetyltransferase subunit MAK10, Maintenance of killer protein 10, N-alpha-acetyltransferase, 35 NatC auxiliary subunit, N-terminal acetyltransferase C complex subunit MAK10, ...
 
 
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Disease relevance of MAK10

  • We have isolated MAK10 from selected phage lambda genomic DNA clones that map near MAK10 [1].
 

High impact information on MAK10

  • Elimination of VLPs in the original porinless strain by introduction of the mak10 or the mak3 mutation increased the respiratory defect and prolonged its lag phase on nonfermentable carbon sources [2].
  • In this paper, we show that mutations in mak10 or the pet18 locus, which result in temperature-dependent replication of L-A dsRNA in vivo, also result in instability of the L-A dsRNA-containing (major class) viruslike particles in vitro [3].
  • These results suggest that the mitochondrial genome and L-A dsRNA compete for the MAK10 protein [1].
  • Using MAK10-lacZ fusions we show that MAK10 is expressed at a very low level and that it is glucose repressed [1].
  • MAK10, a glucose-repressible gene necessary for replication of a dsRNA virus of Saccharomyces cerevisiae, has T cell receptor alpha-subunit motifs [1].
 

Biological context of MAK10

References

 
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