Gene Review:
PDLIM4 - PDZ and LIM domain 4
Homo sapiens
Synonyms:
LIM protein RIL, PDZ and LIM domain protein 4, RIL, Reversion-induced LIM protein
- PDLIM4 repression by hypermethylation as a potential biomarker for prostate cancer. Vanaja, D.K., Ballman, K.V., Morlan, B.W., Cheville, J.C., Neumann, R.M., Lieber, M.M., Tindall, D.J., Young, C.Y. Clin. Cancer Res. (2006)
- In vivo distribution of recombinant interleukin-2-activated autologous lymphocytes administered by intra-arterial infusion in patients with renal cell carcinoma. Morita, T., Yonese, Y., Minato, N. J. Natl. Cancer Inst. (1987)
- Murine lymphokine-activated killer (LAK) cells: phenotypic characterization of the precursor and effector cells. Yang, J.C., Mulé, J.J., Rosenberg, S.A. J. Immunol. (1986)
- Adoptive immunotherapy of murine hepatic metastases with lymphokine activated killer (LAK) cells and recombinant interleukin 2 (RIL 2) can mediate the regression of both immunogenic and nonimmunogenic sarcomas and an adenocarcinoma. Lafreniere, R., Rosenberg, S.A. J. Immunol. (1985)
- In vivo administration of purified human interleukin 2. II. Half life, immunologic effects, and expansion of peripheral lymphoid cells in vivo with recombinant IL 2. Lotze, M.T., Matory, Y.L., Ettinghausen, S.E., Rayner, A.A., Sharrow, S.O., Seipp, C.A., Custer, M.C., Rosenberg, S.A. J. Immunol. (1985)
- RIL, a LIM gene on 5q31, is silenced by methylation in cancer and sensitizes cancer cells to apoptosis. Boumber, Y.A., Kondo, Y., Chen, X., Shen, L., Gharibyan, V., Konishi, K., Estey, E., Kantarjian, H., Garcia-Manero, G., Issa, J.P. Cancer Res. (2007)
- PDZ motifs in PTP-BL and RIL bind to internal protein segments in the LIM domain protein RIL. Cuppen, E., Gerrits, H., Pepers, B., Wieringa, B., Hendriks, W. Mol. Biol. Cell (1998)
- The anti-tumor efficacy of lymphokine-activated killer cells and recombinant interleukin 2 in vivo: direct correlation between reduction of established metastases and cytolytic activity of lymphokine-activated killer cells. Mulé, J.J., Yang, J., Shu, S., Rosenberg, S.A. J. Immunol. (1986)
- The human RIL gene: mapping to human chromosome 5q31.1, genomic organization and alternative transcripts. Bashirova, A.A., Markelov, M.L., Shlykova, T.V., Levshenkova, E.V., Alibaeva, R.A., Frolova, E.I. Gene (1998)
- Association of genetic variation of the RIL gene, encoding a PDZ-LIM domain protein and localized in 5q31.1, with low bone mineral density in adult Japanese women. Omasu, F., Ezura, Y., Kajita, M., Ishida, R., Kodaira, M., Yoshida, H., Suzuki, T., Hosoi, T., Inoue, S., Shiraki, M., Orimo, H., Emi, M. J. Hum. Genet. (2003)
- The PDZ-LIM protein RIL modulates actin stress fiber turnover and enhances the association of alpha-actinin with F-actin. Vallenius, T., Scharm, B., Vesikansa, A., Luukko, K., Schäfer, R., Mäkelä, T.P. Exp. Cell Res. (2004)
- Actin/alpha-actinin-dependent transport of AMPA receptors in dendritic spines: role of the PDZ-LIM protein RIL. Schulz, T.W., Nakagawa, T., Licznerski, P., Pawlak, V., Kolleker, A., Rozov, A., Kim, J., Dittgen, T., Köhr, G., Sheng, M., Seeburg, P.H., Osten, P. J. Neurosci. (2004)
- Structure, dynamics and binding characteristics of the second PDZ domain of PTP-BL. Walma, T., Spronk, C.A., Tessari, M., Aelen, J., Schepens, J., Hendriks, W., Vuister, G.W. J. Mol. Biol. (2002)
- The zyxin-related protein TRIP6 interacts with PDZ motifs in the adaptor protein RIL and the protein tyrosine phosphatase PTP-BL. Cuppen, E., van Ham, M., Wansink, D.G., de Leeuw, A., Wieringa, B., Hendriks, W. Eur. J. Cell Biol. (2000)
- A cholera-coli related enterotoxin production by different Shigella species. Panigrahi, D., Nayak, N., Ganguly, N.K., Roy, P., Sehgal, R. Indian journal of pathology & microbiology. (1993)