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pscC  -  type III secretion outer membrane protein...

Pseudomonas aeruginosa PAO1

 
 
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High impact information on pscC

  • Strains with mutations in the exsA gene, which encodes a type III regulatory protein, or pscC, which encodes an essential component of the secretion apparatus, were also significantly attenuated [1].
 

Biological context of pscC

  • To ascertain the role of proteins secreted by the type III secretion system (TTSS) in HUVEC killing, defective mutants of PAO1 and PA103 were constructed by plasmid insertion in exsA or pscC genes [2].

References

  1. An adenylate cyclase-controlled signaling network regulates Pseudomonas aeruginosa virulence in a mouse model of acute pneumonia. Smith, R.S., Wolfgang, M.C., Lory, S. Infect. Immun. (2004) [Pubmed]
  2. Type III secretion-mediated killing of endothelial cells by Pseudomonas aeruginosa. Saliba, A.M., Filloux, A., Ball, G., Silva, A.S., Assis, M.C., Plotkowski, M.C. Microb. Pathog. (2002) [Pubmed]
 
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