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Gene Review:

zwf - glucose-6-phosphate 1-dehydrogenase

Streptococcus pneumoniae R6

Ip, M. et al., Brigante, G. et al.

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Disease relevance of zwf

Use of the housekeeping genes, gdh (zwf) and gki, in multilocus sequence typing to differentiate Streptococcus pneumoniae from Streptococcus mitis and Streptococcus oralis [1].
Polymerase chain reaction and sequencing of the housekeeping genes, gdh (zwf) and gki, based on the primers and alleles from multilocus sequence typing can be used to delineate and support the identity of clinical isolates of Streptococcus pneumoniae and differentiate from the closely related Streptococcus mitis and Streptococcus oralis [1].

High impact information on zwf

Molecular methods (sequencing of 16S rRNA and zwf and gki genes and ddl gene amplification) were used to investigate discordant results [2].

References

Use of the housekeeping genes, gdh (zwf) and gki, in multilocus sequence typing to differentiate Streptococcus pneumoniae from Streptococcus mitis and Streptococcus oralis. Ip, M., Chi, F., Chau, S.S., Hui, M., Tang, J., Chan, P.K. Diagn. Microbiol. Infect. Dis. (2006) [Pubmed]
Use of the Phoenix Automated System for Identification of Streptococcus and Enterococcus spp. Brigante, G., Luzzaro, F., Bettaccini, A., Lombardi, G., Meacci, F., Pini, B., Stefani, S., Toniolo, A. J. Clin. Microbiol. (2006) [Pubmed]

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