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Gene Review:

nanB - neuraminidase B

Streptococcus pneumoniae R6

Berry, A.M. et al., Pettigrew, M.M. et al.

Pettigrew, Fennie, York, Daniels, Ghaffar,

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Disease relevance of nanB

Cloning and characterization of nanB, a second Streptococcus pneumoniae neuraminidase gene, and purification of the NanB enzyme from recombinant Escherichia coli [1].

High impact information on nanB

We found 149 STs among our S. pneumoniae isolates. nanA was present in all strains, while nanB and nanC were present in 96% and 51% of isolates, respectively [2].

References

Cloning and characterization of nanB, a second Streptococcus pneumoniae neuraminidase gene, and purification of the NanB enzyme from recombinant Escherichia coli. Berry, A.M., Lock, R.A., Paton, J.C. J. Bacteriol. (1996) [Pubmed]
Variation in the presence of neuraminidase genes among Streptococcus pneumoniae isolates with identical sequence types. Pettigrew, M.M., Fennie, K.P., York, M.P., Daniels, J., Ghaffar, F. Infect. Immun. (2006) [Pubmed]

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