Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

flgK - flagellar hook-filament junction protein 1

Escherichia coli str. K-12 substr. MG1655

Synonyms: ECK1067, JW1069, flaS

Van Way, S.M. et al., Homma, M. et al.

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Disease relevance of flgK

The antibodies against HAP1 and HAP3 also specifically reacted with the gene products of flaS and flaT of Escherichia coli, respectively [1].

High impact information on flgK

These eight mutations lie between -37 and -22 within an 18-bp sequence that matches, at 11 nucleotides, sequences in the 5' regions of the flaQR (flaS locus) and fliLM operons, which are also expressed early and occupy a high level in the regulatory hierarchy (A. Dingwall, A. Zhuang, K. Quon, and L. Shapiro, J. Bacteriol. 174:1760-1768, 1992) [2].

References

Structural genes for flagellar hook-associated proteins in Salmonella typhimurium. Homma, M., Kutsukake, K., Iino, T. J. Bacteriol. (1985) [Pubmed]
Identification of the promoter and a negative regulatory element, ftr4, that is needed for cell cycle timing of fliF operon expression in Caulobacter crescentus. Van Way, S.M., Newton, A., Mullin, A.H., Mullin, D.A. J. Bacteriol. (1993) [Pubmed]

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