The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Gene Review

fliD  -  flagellar filament capping protein

Escherichia coli str. K-12 substr. MG1655

Synonyms: ECK1923, JW1909, flbC, rfs
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of fliD


High impact information on fliD

  • Flagellar growth does not occur in fliD-deficient mutants because flagellin monomers transported through the central channel of the flagellum leak out without polymerizing at the distal end [2].
  • In region III, a previously unidentified gene flbC was located between hag and flaN [3].
  • Previous sequence analysis of this operon in both organisms has revealed that the fliD gene constitutes an operon together with two additional genes, fliS and fliT [1].

Other interactions of fliD

  • We have found that fliD, the last known gene in region IIIa, is immediately followed by two additional genes, both necessary for flagellation, which we have designated fliS and fliT [4].


  1. Functional analysis of the flagellar genes in the fliD operon of Salmonella typhimurium. Yokoseki, T., Kutsukake, K., Ohnishi, K., Iino, T. Microbiology (Reading, Engl.) (1995) [Pubmed]
  2. Assembly characteristics of flagellar cap protein HAP2 of Salmonella: decamer and pentamer in the pH-sensitive equilibrium. Imada, K., Vonderviszt, F., Furukawa, Y., Oosawa, K., Namba, K. J. Mol. Biol. (1998) [Pubmed]
  3. Definition of additional flagellar genes in Escherichia coli K12. Komeda, Y., Kutsukake, K., Iino, T. Genetics (1980) [Pubmed]
  4. Subdivision of flagellar region III of the Escherichia coli and Salmonella typhimurium chromosomes and identification of two additional flagellar genes. Kawagishi, I., Müller, V., Williams, A.W., Irikura, V.M., Macnab, R.M. J. Gen. Microbiol. (1992) [Pubmed]
WikiGenes - Universities