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Gene Review:

flgH - flagellar protein of basal-body outer...

Escherichia coli str. K-12 substr. MG1655

Synonyms: ECK1064, JW5153, flaY

Kondoh, H. et al., Kaplan, J.B. et al., Komeda, Y. et al., Dingwall, A. et al.

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Disease relevance of flgH

The definition of region I fla genes and their transcriptional relationships were confirmed by genetic tests with hybrid A phage carrying fla genes in this region [1].
The flbN-encoded protein has 30.8% identity with the protein encoded by the Salmonella typhimurium basal body L-ring gene, flgH [2].
Deletion and amber mutants of fla loci in Escherichia coli K-12 [3].
In addition, strains with deletions of the fla genes in the his-uvrC region were isolated from high-temperature survivors of a lambda cI857 lysogen in which the prophage is located between his and fla [3].

High impact information on flgH

The entire promoter region and an upstream consensus sequence that might be a regulatory element for the flaY gene lies within the carboxyl-terminal coding sequence of the flaE gene [4].

References

Genetic analysis of Escherichia coli K-12 region I flagellar mutants. Komeda, Y., Silverman, M., Simon, M. J. Bacteriol. (1977) [Pubmed]
Identification of a Caulobacter basal body structural gene and a cis-acting site required for activation of transcription. Dingwall, A., Gober, J.W., Shapiro, L. J. Bacteriol. (1990) [Pubmed]
Deletion and amber mutants of fla loci in Escherichia coli K-12. Kondoh, H., Ozeki, H. Genetics (1976) [Pubmed]
Temporal regulation and overlap organization of two Caulobacter flagellar genes. Kaplan, J.B., Dingwall, A., Bryan, R., Champer, R., Shapiro, L. J. Mol. Biol. (1989) [Pubmed]

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