The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Gene Review

aroB  -  3-dehydroquinate synthase

Escherichia coli str. K-12 substr. MG1655

Synonyms: ECK3376, JW3352
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of aroB


High impact information on aroB


Chemical compound and disease context of aroB


Biological context of aroB


Associations of aroB with chemical compounds


Other interactions of aroB

  • We present evidence for translational coupling between aroB and urf74.3 and also between rpe and gph [1].
  • This observed linkage of the gerC genes with the ndk, aroC and aroB genes has been similarly observed in B. subtilis [18].
  • Downstream of aroB a region of inverted repeats and a gene showing high homology to yafJ of E. coli has been identified [2].
  • Further analysis revealed that the ftsD220 mapped at min 73 and that it is linked to cysG (6%) and to aroB (39%) [19].
  • The presence of the aroB gene and the putative tgt homologue in unrelated H. pylori strains was confirmed by Southern blot hybridization and by polymerase chain reaction with specific primers [4].

Analytical, diagnostic and therapeutic context of aroB


  1. Characterization of three genes in the dam-containing operon of Escherichia coli. Lyngstadaas, A., Løbner-Olesen, A., Boye, E. Mol. Gen. Genet. (1995) [Pubmed]
  2. Cloning and characterisation of the Neisseria gonorrhoeae aroB gene. Barten, R., Meyer, T.F. Mol. Gen. Genet. (1998) [Pubmed]
  3. Cloning and analysis of the aroB gene encoding dehydroquinate synthase from Corynebacterium glutamicum. Han, M.A., Lee, H.S., Cheon, C.I., Min, K.H., Lee, M.S. Can. J. Microbiol. (1999) [Pubmed]
  4. Cloning and functional characterization of the genes encoding 3-dehydroquinate synthase (aroB) and tRNA-guanine transglycosylase (tgt) from Helicobacter pylori. Bereswill, S., Fassbinder, F., Völzing, C., Haas, R., Reuter, K., Ficner, R., Kist, M. Med. Microbiol. Immunol. (Berl.) (1997) [Pubmed]
  5. Unique biosynthesis of dehydroquinic acid? Woodard, R.W. Bioorg. Chem. (2004) [Pubmed]
  6. Overinitiation of chromosome replication in the Escherichia coli dnaAcos mutant depends on activation of oriC function by the dam gene product. Katayama, T., Akimitsu, N., Mizushima, T., Miki, T., Sekimizu, K. Mol. Microbiol. (1997) [Pubmed]
  7. Dehydroquinate synthase from Escherichia coli: purification, cloning, and construction of overproducers of the enzyme. Frost, J.W., Bender, J.L., Kadonaga, J.T., Knowles, J.R. Biochemistry (1984) [Pubmed]
  8. Hemin binding, functional expression, and complementation analysis of Pap 31 from Bartonella henselae. Zimmermann, R., Kempf, V.A., Schiltz, E., Oberle, K., Sander, A. J. Bacteriol. (2003) [Pubmed]
  9. Helicobacter pylori ribBA-mediated riboflavin production is involved in iron acquisition. Worst, D.J., Gerrits, M.M., Vandenbroucke-Grauls, C.M., Kusters, J.G. J. Bacteriol. (1998) [Pubmed]
  10. Cloning of a cDNA encoding a 3-dehydroquinate synthase from a higher plant, and analysis of the organ-specific and elicitor-induced expression of the corresponding gene. Bischoff, M., Rösler, J., Raesecke, H.R., Görlach, J., Amrhein, N., Schmid, J. Plant Mol. Biol. (1996) [Pubmed]
  11. Iron supply of Escherichia coli with polymer-bound ferricrocin. Coulton, J.W., Naegeli, H.U., Braun, V. Eur. J. Biochem. (1979) [Pubmed]
  12. A SitABCD homologue from an avian pathogenic Escherichia coli strain mediates transport of iron and manganese and resistance to hydrogen peroxide. Sabri, M., Léveillé, S., Dozois, C.M. Microbiology (Reading, Engl.) (2006) [Pubmed]
  13. The complete amino acid sequence of 3-dehydroquinate synthase of Escherichia coli K12. Millar, G., Coggins, J.R. FEBS Lett. (1986) [Pubmed]
  14. The Escherichia coli dam gene is expressed as a distal gene of a new operon. Jonczyk, P., Hines, R., Smith, D.W. Mol. Gen. Genet. (1989) [Pubmed]
  15. Biochemical and genetic characterization of nirB mutants of Escherichia coli K 12 pleiotropically defective in nitrite and sulphite reduction. Cole, J.A., Newman, B.M., White, P. J. Gen. Microbiol. (1980) [Pubmed]
  16. Expression of the Escherichia coli dam gene. Løbner-Olesen, A., Boye, E., Marinus, M.G. Mol. Microbiol. (1992) [Pubmed]
  17. Microbial synthesis of p-hydroxybenzoic acid from glucose. Barker, J.L., Frost, J.W. Biotechnol. Bioeng. (2001) [Pubmed]
  18. Chorismate synthase from Staphylococcus aureus. Horsburgh, M.J., Foster, T.J., Barth, P.T., Coggins, J.R. Microbiology (Reading, Engl.) (1996) [Pubmed]
  19. Fts insertional mutant of Salmonella typhimurium. Cerquetti, M.C., Brawer, R., Gerdes, C.A., Gherardi, M.M., Sordelli, D.O. FEMS Microbiol. Lett. (1995) [Pubmed]
  20. Molecular cloning and functional analysis of the cysG and nirB genes of Escherichia coli K12, two closely-linked genes required for NADH-dependent nitrite reductase activity. Macdonald, H., Cole, J. Mol. Gen. Genet. (1985) [Pubmed]
WikiGenes - Universities