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Gene Review:

lyxK - L-xylulose kinase

Escherichia coli str. K-12 substr. MG1655

Synonyms: ECK3569, JW3552, lyx, xylK, yiaP

Sánchez, J.C. et al.

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High impact information on lyx

The gene encoding L-xylulose kinase was mapped in the 80.2 min region of the chromosome by conjugation and transduction [1].
L-Xylulose kinase was purified to homogeneity and found to be a dimer of two subunits of 55 kDa, highly specific for L-xylulose with a Km of 0.8 mM, a Vmax of 33 mumol/min/mg, and an optimum pH of 8 [1].

Analytical, diagnostic and therapeutic context of lyx

4. Physical (thin layer chromatography) and spectroscopic (nuclear magnetic resonance and optical rotation) characterization of the product of L-xylulose kinase indicated that the enzyme phosphorylated the sugar at position 5 [1].

References

Activation of a cryptic gene encoding a kinase for L-xylulose opens a new pathway for the utilization of L-lyxose by Escherichia coli. Sánchez, J.C., Gímenez, R., Schneider, A., Fessner, W.D., Baldomà, L., Aguilar, J., Badía, J. J. Biol. Chem. (1994) [Pubmed]

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