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Gene Review:

rhlB - ATP-dependent RNA helicase

Escherichia coli str. K-12 substr. MG1655

Synonyms: ECK3772, JW3753

Sharma, R.C. et al., Kalman, M. et al.

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Disease relevance of rhlB

A newly recognized gene we name rhlB, after RNA helicase-like genes, has been found in the 85-minute region of the Escherichia coli chromosome [1].

High impact information on rhlB

An additional mmrA mutation or growth retardation by valine blocked both this extra DNA synthesis in RM, and the inhibitory effect of RM on survival [2].

References

rhlB, a new Escherichia coli K-12 gene with an RNA helicase-like protein sequence motif, one of at least five such possible genes in a prokaryote. Kalman, M., Murphy, H., Cashel, M. New Biol. (1991) [Pubmed]
A mechanism for rich-medium inhibition of the repair of daughter-strand gaps in the deoxyribonucleic acid of UV-irradiated Escherichia coli K12 uvrA. Sharma, R.C., Smith, K.C. Mutat. Res. (1985) [Pubmed]

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