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Gene Review

plsB  -  glycerol-3-phosphate O-acyltransferase

Escherichia coli str. K-12 substr. MG1655

Synonyms: ECK4033, JW4001
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Disease relevance of plsB


High impact information on plsB


Chemical compound and disease context of plsB


Biological context of plsB


Anatomical context of plsB

  • This method also allowed measurement of the specific activities of the glycerol-P acyltransferase in membranes from a wild type E. coli strain and from plasmid-containing strains which express the plsB gene product to different extents [10].

Associations of plsB with chemical compounds


Analytical, diagnostic and therapeutic context of plsB


  1. The DNA sequences encoding plsB and dgk loci of Escherichia coli. Lightner, V.A., Bell, R.M., Modrich, P. J. Biol. Chem. (1983) [Pubmed]
  2. Acyl-phosphates initiate membrane phospholipid synthesis in Gram-positive pathogens. Lu, Y.J., Zhang, Y.M., Grimes, K.D., Qi, J., Lee, R.E., Rock, C.O. Mol. Cell (2006) [Pubmed]
  3. Polypeptide structure of germin as deduced from cDNA sequencing. Dratewka-Kos, E., Rahman, S., Grzelczak, Z.F., Kennedy, T.D., Murray, R.K., Lane, B.G. J. Biol. Chem. (1989) [Pubmed]
  4. Crystalline arrays of the Escherichia coli sn-glycerol-3-phosphate acyltransferase, an integral membrane protein. Wilkison, W.O., Walsh, J.P., Corless, J.M., Bell, R.M. J. Biol. Chem. (1986) [Pubmed]
  5. Turnover of fatty acids in the 1-position of phosphatidylethanolamine in Escherichia coli. Rock, C.O. J. Biol. Chem. (1984) [Pubmed]
  6. Partial NH2- and COOH-terminal sequence and cyanogen bromide peptide analysis of Escherichia coli sn-glycerol-3-phosphate acyltransferase. Green, P.R., Vanaman, T.C., Modrich, P., Bell, R.M. J. Biol. Chem. (1983) [Pubmed]
  7. Analysis of amino acid motifs diagnostic for the sn-glycerol-3-phosphate acyltransferase reaction. Lewin, T.M., Wang, P., Coleman, R.A. Biochemistry (1999) [Pubmed]
  8. A missense mutation accounts for the defect in the glycerol-3-phosphate acyltransferase expressed in the plsB26 mutant. Heath, R.J., Rock, C.O. J. Bacteriol. (1999) [Pubmed]
  9. Membrane charge and curvature determine interaction with acyl-CoA binding protein (ACBP) and fatty acyl-CoA targeting. Chao, H., Martin, G.G., Russell, W.K., Waghela, S.D., Russell, D.H., Schroeder, F., Kier, A.B. Biochemistry (2002) [Pubmed]
  10. Efficiency of reconstitution of the membrane-associated sn-glycerol 3-phosphate acyltransferase of Escherichia coli. Scheideler, M.A., Bell, R.M. J. Biol. Chem. (1986) [Pubmed]
  11. Fatty acid metabolism in sn-glycerol-3-phosphate acyltransferase (plsB) mutants. Cooper, C.L., Jackowski, S., Rock, C.O. J. Bacteriol. (1987) [Pubmed]
  12. Enzymatic sorting of bacterial colonies on filter paper replicas: detection of labile activities. Bulawa, C.E., Ganong, B.R., Sparrow, C.P., Raetz, C.R. J. Bacteriol. (1981) [Pubmed]
  13. Adaptation to a fish oil diet before inducing sepsis in rats prevents fatty infiltration of the liver. Lanza-Jacoby, S., Smythe, C., Phetteplace, H., Tabares, A. JPEN. Journal of parenteral and enteral nutrition. (1992) [Pubmed]
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