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Gene Review

tsf  -  elongation factor Ts

Escherichia coli O157:H7 str. EDL933

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High impact information on tsf

  • The effects are attributed to the interference of the mutations with the EF-Ts-induced movements of the P-loop of EF-Tu and changes at the domain 1/3 interface, leading to the release of the beta-phosphate group of GTP/GDP [1].


  1. The importance of P-loop and domain movements in EF-Tu for guanine nucleotide exchange. Dahl, L.D., Wieden, H.J., Rodnina, M.V., Knudsen, C.R. J. Biol. Chem. (2006) [Pubmed]
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