Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Editor

Personal info

View

About

Terms

Javascript disabled

Please enable Javascript support in your browser to use this application.

Instructions on how to enable JavaScript on different browsers can be found here: http://www.google.com/support/bin/answer.py?answer=23852.

[edit this page]

Gene Review:

priA - primosome assembly protein PriA

Escherichia coli O157:H7 str. EDL933

Wei, J.R. et al., Kim, S.H. et al.

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of priA

In comparison with wild-type E. coli strain, over-expression of spnT in an E. coli priA and dnaC double-mutant strain did not lead to the aberrant cell morphology phenotypes, suggesting SpnT may act through the recombination-dependent DNA replication system [1].

High impact information on priA

Mutations in priA and recG increased or decreased deletion rates, but repeats were still greatly stabilized in the chromosome [2].

References

Regulatory roles of spnT, a novel gene located within transposon TnTIR. Wei, J.R., Soo, P.C., Horng, Y.T., Hsieh, S.C., Tsai, Y.H., Swift, S., Withers, H., Williams, P., Lai, H.C. Biochem. Biophys. Res. Commun. (2006) [Pubmed]
(CAG){middle dot}(CTG) Repeats Associated with Neurodegenerative Diseases Are Stable in the Escherichia coli Chromosome. Kim, S.H., Pytlos, M.J., Rosche, W.A., Sinden, R.R. J. Biol. Chem. (2006) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.