Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

marR - MarR family transcriptional regulator

Escherichia coli O157:H7 str. EDL933

Nicoloff, H. et al., Dorsey, C.W. et al.

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Disease relevance of marR

Cloning and introduction of the ohr and marR ORFs into Escherichia coli was associated with an increase in resistance to CHP and t-BHP [1].

High impact information on marR

The phenotype was linked to insertion sequence (IS) insertions in marR or acrR or unstable large tandem genomic amplifications which included acrAB and which were bordered by IS3 or IS5 sequences [2].

References

Sequence and organization of pMAC, an Acinetobacter baumannii plasmid harboring genes involved in organic peroxide resistance. Dorsey, C.W., Tomaras, A.P., Actis, L.A. Plasmid (2006) [Pubmed]
Increased Genome Instability in Escherichia coli lon Mutants: Relation to Emergence of Multiple-Antibiotic-Resistant (Mar) Mutants Caused by Insertion Sequence Elements and Large Tandem Genomic Amplifications. Nicoloff, H., Perreten, V., Levy, S.B. Antimicrob. Agents Chemother. (2007) [Pubmed]

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