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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

NSm  -  nonstructural protein

Watermelon silver mottle virus

 
 
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Disease relevance of NSm

  • The nonstructural NSm protein of tomato spotted wilt tospovirus (TSWV) represents a putative viral movement protein involved in cell-to-cell movement of nonenveloped ribonucleocapsid structures [1].
  • The 33.6-kDa nonstructural (NSM) protein gene, located on the ambisense M RNA segment of tomato spotted wilt virus (TSWV), was cloned and expressed using the Escherichia coli pET-11t expression system [2].
 

High impact information on NSm

  • The expression and subcellular location of the 33.6-kDa nonstructural protein NSm of tomato spotted wilt virus (TSWV) was analyzed in Nicotiana rustica plants and protoplasts as a function of time [3].
  • Using this technique, structural and nonstructural proteins of TSWV were readily detected and specifically labelled in cells of the insect vector, the western flower thrips, Frankliniella occidentalis (Pergande), and in infected cells of the plant species, Emilia sonchifolia L [4].
 

Analytical, diagnostic and therapeutic context of NSm

References

  1. The movement protein NSm of tomato spotted wilt tospovirus (TSWV): RNA binding, interaction with the TSWV N protein, and identification of interacting plant proteins. Soellick, T., Uhrig, J.F., Bucher, G.L., Kellmann, J.W., Schreier, P.H. Proc. Natl. Acad. Sci. U.S.A. (2000) [Pubmed]
  2. Expression and subcellular location of the NSM protein of tomato spotted wilt virus (TSWV), a putative viral movement protein. Kormelink, R., Storms, M., Van Lent, J., Peters, D., Goldbach, R. Virology (1994) [Pubmed]
  3. The nonstructural NSm protein of tomato spotted wilt virus induces tubular structures in plant and insect cells. Storms, M.M., Kormelink, R., Peters, D., Van Lent, J.W., Goldbach, R.W. Virology (1995) [Pubmed]
  4. Rapid fixation and embedding method for immunocytochemical studies of tomato spotted wilt tospovirus (TSWV) in plant and insect tissues. Westcot, D.M., Ullman, D.E., Sherwood, J.L., Cantone, F.A., German, T.L. Microsc. Res. Tech. (1993) [Pubmed]
  5. Impact of early-season thrips management on reducing the risks of spotted wilt virus and suppressing aphid populations in Flue-cured tobacco. McPherson, R.M., Stephenson, M.G., Lahue, S.S., Mullis, S.W. J. Econ. Entomol. (2005) [Pubmed]
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