Gene Review:
Dpyd - dihydropyrimidine dehydrogenase
Mus musculus
Synonyms:
AI315208, DHPDHase, DPD, Dihydrothymine dehydrogenase, Dihydrouracil dehydrogenase, ...
- Antitumor effect of combination of S-1 and docetaxel on the human breast cancer xenograft transplanted into SCID mice. Suto, A., Kubota, T., Fukushima, M., Ikeda, T., Takeshita, T., Ohmiya, H., Kitajima, M. Oncol. Rep. (2006)
- Inactivation of botulinum and tetanus toxins by chelators. Bhattacharyya, S.D., Sugiyama, H. Infect. Immun. (1989)
- Augmentation of the antitumor activity of capecitabine by a tumor selective dihydropyrimidine dehydrogenase inhibitor, RO0094889. Endo, M., Miwa, M., Eda, H., Ura, M., Tanimura, H., Ishikawa, T., Miyazaki-Nose, T., Hattori, K., Shimma, N., Yamada-Okabe, H., Ishitsuka, H. Int. J. Cancer (2003)
- Study of in vitro and in vivo effects of 1,6-Bis[4-(4-amino-3-hydroxyphenoxy)phenyl]diamantane (DPD), a novel cytostatic and differentiation inducing agent, on human colon cancer cells. Wang, J.J., Chang, Y.F., Chern, Y.T., Chi, C.W. Br. J. Cancer (2003)
- Pyrimidine base degradation in cultured murine C-1300 neuroblastoma cells and in situ tumors. Tuchman, M., O'Dea, R.F., Ramnaraine, M.L., Mirkin, B.L. J. Clin. Invest. (1988)
- 5-Ethynyluracil (776C85): a potent modulator of the pharmacokinetics and antitumor efficacy of 5-fluorouracil. Baccanari, D.P., Davis, S.T., Knick, V.C., Spector, T. Proc. Natl. Acad. Sci. U.S.A. (1993)
- In vivo effect of 5-ethynyluracil on 5-fluorouracil metabolism determined by 19F nuclear magnetic resonance spectroscopy. Adams, E.R., Leffert, J.J., Craig, D.J., Spector, T., Pizzorno, G. Cancer Res. (1999)
- Retroviral transduction of human dihydropyrimidine dehydrogenase cDNA confers resistance to 5-fluorouracil in murine hematopoietic progenitor cells and human CD34+-enriched peripheral blood progenitor cells. Takebe, N., Zhao, S.C., Ural, A.U., Johnson, M.R., Banerjee, D., Diasio, R.B., Bertino, J.R. Cancer Gene Ther. (2001)
- CPT-11 alters the circadian rhythm of dihydropyrimidine dehydrogenase mRNA in mouse liver. Shimizu, M., Tamura, T., Yamada, Y., Akiyama, Y., Saijo, N., Nishio, K. Jpn. J. Cancer Res. (2001)
- Dihydropyrimidine dehydrogenase circadian rhythm in mouse liver: comparison between enzyme activity and gene expression. Porsin, B., Formento, J.L., Filipski, E., Etienne, M.C., Francoual, M., Renée, N., Magné, N., Lévi, F., Milano, G. Eur. J. Cancer (2003)
- Regulation of dihydropyrimidine dehydrogenase gene expression in regenerating mouse liver. Yamada, H., Fukushima, M., Koizumi, K., Katakura, H., Nakanishi, H., Teshima, S., Kamiyama, Y., Ikenaka, K. Int. J. Oncol. (2003)
- 5-Ethynyluracil (776C85): inactivation of dihydropyrimidine dehydrogenase in vivo. Spector, T., Harrington, J.A., Porter, D.J. Biochem. Pharmacol. (1993)
- Persistent twenty-four hour changes in liver and bone marrow despite suprachiasmatic nuclei ablation in mice. Filipski, E., King, V.M., Etienne, M.C., Li, X., Claustrat, B., Granda, T.G., Milano, G., Hastings, M.H., Lévi, F. Am. J. Physiol. Regul. Integr. Comp. Physiol. (2004)
- Positive correlation between the efficacy of capecitabine and doxifluridine and the ratio of thymidine phosphorylase to dihydropyrimidine dehydrogenase activities in tumors in human cancer xenografts. Ishikawa, T., Sekiguchi, F., Fukase, Y., Sawada, N., Ishitsuka, H. Cancer Res. (1998)