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MeSH Review

Radicular Cyst

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Disease relevance of Radicular Cyst


High impact information on Radicular Cyst


Chemical compound and disease context of Radicular Cyst

  • In tissue sections the highest amount of tryptase-positive staining was observed in radicular cysts (mean 6.2% of reference area) and the lowest amount in keratocysts (mean 2.1% of reference area, P < 0.01) [9].
  • In addition, another section from each radicular cyst specimen was stained with hematoxylin and eosin to assess the presence of inflammatory infiltrates [8].
  • By contrast, succinate dehydrogenase activity was significantly higher in radicular cyst linings (p < 0.03) [2].
  • The distribution of subunit A of Factor XIII (FXIIIa) and of collagenous components was investigated by the avidin-biotin-peroxidase complex (ABC) method for FXIIIa and by the Sirius red F3BA method, respectively, in 43 cases of radicular cysts [10].
  • 3. Anti-human apo B antibody inhibited cholesterol-binding activity in radicular cyst fluid [11].

Biological context of Radicular Cyst


Anatomical context of Radicular Cyst


Gene context of Radicular Cyst


Analytical, diagnostic and therapeutic context of Radicular Cyst


  1. Interleukin-1alpha-dependent regulation of matrix metalloproteinase-9(MMP-9) secretion and activation in the epithelial cells of odontogenic jaw cysts. Kubota, Y., Ninomiya, T., Oka, S., Takenoshita, Y., Shirasuna, K. J. Dent. Res. (2000) [Pubmed]
  2. In situ determination of different dehydrogenase activity profiles in the linings of odontogenic keratocysts and radicular cysts. Mason, G.I., Matthews, J.B. Histochem. J. (1996) [Pubmed]
  3. Epidermal growth factor receptor in odontogenic cysts and tumors. Shrestha, P., Yamada, K., Higashiyama, H., Takagi, H., Mori, M. J. Oral Pathol. Med. (1992) [Pubmed]
  4. Heat shock protein 27 expression in the epithelium of periapical lesions. Leonardi, R., Villari, L., Caltabiano, M., Travali, S. Journal of endodontics. (2001) [Pubmed]
  5. Immunostaining of involucrin in odontogenic epithelial tumors and cysts. Yamada, K., Tatemoto, Y., Okada, Y., Mori, M. Oral Surg. Oral Med. Oral Pathol. (1989) [Pubmed]
  6. Levels of GM-CSF, IL-3, and IL-6 in fluid and tissue from human radicular cysts. Gervásio, A.M., Silva, D.A., Taketomi, E.A., Souza, C.J., Sung, S.S., Loyola, A.M. J. Dent. Res. (2002) [Pubmed]
  7. Cytokeratin expression patterns for distinction of odontogenic keratocysts from dentigerous and radicular cysts. Stoll, C., Stollenwerk, C., Riediger, D., Mittermayer, C., Alfer, J. J. Oral Pathol. Med. (2005) [Pubmed]
  8. Immunohistochemical localization of tissue-type plasminogen activator and type I plasminogen activator inhibitor in radicular cysts. Tsai, C.H., Weng, S.F., Yang, L.C., Huang, F.M., Chen, Y.J., Chang, Y.C. J. Oral Pathol. Med. (2004) [Pubmed]
  9. Mast cell-derived tryptase in odontogenic cysts. Teronen, O., Hietanen, J., Lindqvist, C., Salo, T., Sorsa, T., Eklund, K.K., Sommerhoff, C.P., Ylipaavalniemi, P., Konttinen, Y.T. J. Oral Pathol. Med. (1996) [Pubmed]
  10. Distribution of factor XIIIa-containing cells and collagenous components in radicular cysts: histochemic and immunohistochemic studies. Toida, M., Tsai, C.S., Okumura, Y., Tatematsu, N., Oka, N. J. Oral Pathol. Med. (1990) [Pubmed]
  11. Studies on cholesterol accumulation in radicular cyst fluid--origin of heat-stable cholesterol-binding protein. Yashima, M., Ogura, N., Abiko, Y. Int. J. Biochem. (1990) [Pubmed]
  12. PTCH gene altered in dentigerous cysts. Pavelić, B., Levanat, S., Crnić, I., Kobler, P., Anić, I., Manojlović, S., Sutalo, J. J. Oral Pathol. Med. (2001) [Pubmed]
  13. Josamycin concentrations in radicular cysts following a single oral administration. Akimoto, Y., Mochizuki, Y., Uda, A., Omata, H., Saito, S., Kaneko, K., Fujii, A., Yamamoto, H. Gen. Pharmacol. (1993) [Pubmed]
  14. High IL-6 synthesis in cultured fibroblasts isolated from radicular cysts. Kusumi, A., Sakaki, H., Fukui, R., Satoh, H., Kusumi, T., Kimura, H. Arch. Oral Biol. (2004) [Pubmed]
  15. Comparative immunohistochemical study of the presence of mast cells in apical granulomas and periapical cysts: possible role of mast cells in the course of human periapical lesions. de Oliveira Rodini, C., Batista, A.C., Lara, V.S. Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics. (2004) [Pubmed]
  16. Stimulation of interleukin-1 beta production of human dental pulp cells by Porphyromonas endodontalis lipopolysaccharide. Hosoya, S., Matsushima, K. Journal of endodontics. (1997) [Pubmed]
  17. Detection of vascular endothelial growth factor/ vascular permeability factor in periapical lesions. Leonardi, R., Caltabiano, M., Pagano, M., Pezzuto, V., Loreto, C., Palestro, G. Journal of endodontics. (2003) [Pubmed]
  18. Localization of mRNA for inflammatory cytokines in radicular cyst tissue by in situ hybridization, and induction of inflammatory cytokines by human gingival fibroblasts in response to radicular cyst contents. Honma, M., Hayakawa, Y., Kosugi, H., Koizumi, F. J. Oral Pathol. Med. (1998) [Pubmed]
  19. p53 and MDM2 expression in odontogenic cysts and tumours. Carvalhais, J., Aguiar, M., Araújo, V., Araújo, N., Gomez, R. Oral diseases. (1999) [Pubmed]
  20. Immunolocalization of interstitial collagenase (MMP-1) and tissue inhibitor of metalloproteinases-1 (TIMP-1) in radicular cysts. Lin, S.K., Chiang, C.P., Hong, C.Y., Lin, C.P., Lan, W.H., Hsieh, C.C., Kuo, M.Y. J. Oral Pathol. Med. (1997) [Pubmed]
  21. Immunohistochemical localization of cyclooxygenase-2 in radicular cysts. Tsai, C.H., Huang, F.M., Yang, L.C., Chou, M.Y., Chang, Y.C. International endodontic journal. (2002) [Pubmed]
  22. The role of endotoxin and cytokines in the pathogenesis of odontogenic cysts. Meghji, S., Qureshi, W., Henderson, B., Harris, M. Arch. Oral Biol. (1996) [Pubmed]
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