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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review


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Disease relevance of Thrombectomy


High impact information on Thrombectomy

  • This report summarizes our experience with caval thrombectomy and reconstruction that allowed complete removal of all gross tumor in seven patients with malignant occlusion of the retrohepatic inferior vena cava [6].
  • Anticoagulation therapy with heparin or thrombectomy are treatment options [7].
  • In organ chamber studies, endothelium-dependent relaxations to calcium ionophore, but not adenosine diphosphate, were inhibited by an antagonist of nitric oxide production after thrombectomy (P <.05, thrombectomy vs sham- and thrombolysis-treated veins) [8].
  • The sixth patient required two thrombectomies and warfarin [9].
  • Balloon catheter thrombectomy significantly reduced endothelium-dependent relaxations compared with all other groups in response to acetylcholine, bradykinin, and thrombin (p < 0.001) [10].

Chemical compound and disease context of Thrombectomy


Biological context of Thrombectomy


Anatomical context of Thrombectomy


Associations of Thrombectomy with chemical compounds

  • Only 2 (17%) graft limbs had no luminal defects after thrombectomy [21].
  • Heparin (10 units/min) and nitroglycerin (50 micrograms/min) were the agents infused most frequently, for a mean duration of 52 hours after thrombectomy [22].
  • To evaluate the clinical effectiveness of rheolytic thrombectomy in a nonselected population in the glycoprotein IIb/IIIa blockade era, we reviewed clinical, angiographic, and procedural data on 119 patients who underwent 126 consecutive coronary AngioJet procedures (29% in SVGs, and 71% in native coronary arteries) from July 1998 to August 2000 [23].
  • She was treated aggressively with pentobarbital coma, angiography, and thrombectomy and recovered with minimal deficit [24].
  • In 24 patients the method of surgical thrombectomy proved to be effective and they received a preventive dose of Clopidogrel [75 mg per 24h] for 28 days [13].

Gene context of Thrombectomy

  • PURPOSE: To determine if the lyse and wait (L&W) technique with a 4-mg dose of alteplase (tissue plasminogen activator; tPA) is a safe and effective method of declotting dialysis grafts as compared to use of the Arrow-Trerotola Percutaneous Thrombectomy Device (PTD) or the L&W technique with use of urokinase (UK) [25].
  • Current status of percutaneous mechanical thrombectomy. Part III. Present and future applications [26].
  • The use of mechanical thrombectomy devices in the management of acute peripheral arterial occlusive disease [27].
  • Arterialized flow was re-established by hydrodynamic thrombectomy and PTA in 43 of 51 cases (84%) [28].
  • There were 1.188 thrombectomies and 0.222 mechanical problems per 1,000 patient-days prior to the initiation of EPO treatment [29].

Analytical, diagnostic and therapeutic context of Thrombectomy


  1. Central venous septic thrombosis managed by superior vena cava Greenfield filter and venous thrombectomy: a case report. Hoffman, M.J., Greenfield, L.J. J. Vasc. Surg. (1986) [Pubmed]
  2. A strategy of aggressive regional therapy for acute iliofemoral venous thrombosis with contemporary venous thrombectomy or catheter-directed thrombolysis. Comerota, A.J., Aldridge, S.C., Cohen, G., Ball, D.S., Pliskin, M., White, J.V. J. Vasc. Surg. (1994) [Pubmed]
  3. Insertion of the inferior vena cava filter followed by iliofemoral venous thrombectomy for ischemic venous thrombosis. Olearchyk, A.S. J. Vasc. Surg. (1987) [Pubmed]
  4. Regional hyperthermic fibrinolytic perfusion after unsuccessful venous thrombectomy of extensive deep venous thrombosis. Mumme, A., Heinen, W., Geier, B., Maatz, W., Barbera, L., Walterbusch, G. J. Vasc. Surg. (2002) [Pubmed]
  5. Bilateral renal vein and inferior vena cava thrombosis with nephrotic syndrome treated by thrombectomy: case report with 3-year followup. Sutherland, R.D., Anthony, W.A., Martinez, H.E., Guynes, W.A. J. Urol. (1976) [Pubmed]
  6. Suprarenal vena caval occlusion. Principles of operative management. Smith, B.M., Mulherin, J.L., Sawyers, J.L., Turner, B.I., Prager, R.L., Dean, R.H. Ann. Surg. (1984) [Pubmed]
  7. Deep venous thrombosis during pregnancy and after delivery: indications for and results of thrombectomy. Pillny, M., Sandmann, W., Luther, B., Müller, B.T., Tutschek, B., Gerhardt, A., Zotz, R.B., Scharf, R.E. J. Vasc. Surg. (2003) [Pubmed]
  8. Thrombolysis for experimental deep venous thrombosis maintains valvular competence and vasoreactivity. Rhodes, J.M., Cho, J.S., Gloviczki, P., Mozes, G., Rolle, R., Miller, V.M. J. Vasc. Surg. (2000) [Pubmed]
  9. Reduced morbidity and mortality rates of the heparin-induced thrombocytopenia syndrome. Almeida, J.I., Coats, R., Liem, T.K., Silver, D. J. Vasc. Surg. (1998) [Pubmed]
  10. Urokinase treatment preserves endothelial and smooth muscle function in experimental acute arterial thrombosis. Whitley, D., Gloviczki, P., Rhee, R., Tazelaar, H.D., Miller, V. J. Vasc. Surg. (1996) [Pubmed]
  11. Heparin-induced thrombocytopenia with acute aortic and renal thrombosis in a patient treated with low-molecular-weight heparin. Chevalier, J., Ducasse, E., Dasnoy, D., Puppinck, P. European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery. (2005) [Pubmed]
  12. Infrainguinal revascularisation in the era of vein-graft surveillance--do clinical factors influence long-term outcome? Olojugba, D.H., McCarthy, M.J., Reid, A., Varty, K., Naylor, A.R., Bell, P.R., London, N.J. European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery. (1999) [Pubmed]
  13. Preventive administration of Clopidogrel after restoring patency of acute dialysis fistula with surgical thrombectomy. Janicki, K., Pietura, R., Bojarska-Szmygin, A., Gieryng, J., Orłowska, A., Janicka, L. Annales Universitatis Mariae Curie-Skłodowska. Sectio D: Medicina. (2003) [Pubmed]
  14. Heparin, heparin plus ASA and dipyridamole, and arteriovenous fistula as adjuvant methods to prevent rethrombosis after venous thrombectomy. Experimental study in rabbits. Rollo, H.A., Maffei, F.H., Yoshida, W.B., Lastória, S., Curi, P.R., Mattar, L. International angiology : a journal of the International Union of Angiology. (1991) [Pubmed]
  15. Treatment of saphenous vein graft thrombosis with distal protection, thrombectomy, and adenosine prior to reperfusion: a complete approach to preserving microvascular integrity. St John, M., Heldman, A.W. The Journal of invasive cardiology. (2004) [Pubmed]
  16. Left ventricular thrombectomy in a cocaine user with normal coronary arteries. Fortier, S., Demaria, R.G., Pelletier, G.B., Carrier, M., Perrault, L.P. J. Thorac. Cardiovasc. Surg. (2003) [Pubmed]
  17. Surgical repair of superior vena cava syndrome. Calderon, M.C., Lozano, V.M., Jaquez, A., Villaseñor, C. Ann. Thorac. Surg. (2001) [Pubmed]
  18. Use of rheolytic thrombectomy in treatment of acute massive pulmonary embolism. Zeni, P.T., Blank, B.G., Peeler, D.W. Journal of vascular and interventional radiology : JVIR. (2003) [Pubmed]
  19. Should heparin be reversed after carotid endarterectomy? A randomised prospective trial. Fearn, S.J., Parry, A.D., Picton, A.J., Mortimer, A.J., McCollum, C.N. European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery. (1997) [Pubmed]
  20. Balloon catheter-assisted inferior vena cava tumor thrombectomy without thoracotomy. Yanaga, K., Yoshizumi, T., Komori, K., Nishizaki, T., Masuda, M., Sugimachi, K. Hepatogastroenterology (1997) [Pubmed]
  21. An alternative method of salvaging occluded suprainguinal bypass grafts with operative angioscopy and endovascular intervention. White, J.V., Haas, K.S., Comerota, A.J. J. Vasc. Surg. (1993) [Pubmed]
  22. Intragraft drug infusion as an adjunct to balloon catheter thrombectomy for salvage of thrombosed infragenicular vein grafts: a preliminary report. Walsh, D.B., Zwolak, R.M., McDaniel, M.D., Schneider, J.R., Cronenwett, J.L. J. Vasc. Surg. (1990) [Pubmed]
  23. Effectiveness of rheolytic coronary thrombectomy with the AngioJet catheter. Rinfret, S., Katsiyiannis, P.T., Ho, K.K., Cohen, D.J., Baim, D.S., Carrozza, J.P., Laham, R.J. Am. J. Cardiol. (2002) [Pubmed]
  24. Emergency carotid artery thrombectomy for postpartum hemiplegia. Sturm, J.T., Toro, C., Snyder, B.D. The American journal of emergency medicine. (1987) [Pubmed]
  25. Thrombosed hemodialysis grafts: lyse and wait with tissue plasminogen activator or urokinase compared to mechanical thrombolysis with the Arrow-Trerotola Percutaneous Thrombolytic Device. Vogel, P.M., Bansal, V., Marshall, M.W. Journal of vascular and interventional radiology : JVIR. (2001) [Pubmed]
  26. Current status of percutaneous mechanical thrombectomy. Part III. Present and future applications. Sharafuddin, M.J., Hicks, M.E. Journal of vascular and interventional radiology : JVIR. (1998) [Pubmed]
  27. The use of mechanical thrombectomy devices in the management of acute peripheral arterial occlusive disease. Kasirajan, K., Haskal, Z.J., Ouriel, K. Journal of vascular and interventional radiology : JVIR. (2001) [Pubmed]
  28. Hydrodynamic thrombectomy of haemodialysis grafts and fistulae: results of 51 procedures. Vorwerk, D., Schurmann, K., Müller-Leisse, C., Adam, G., Bücker, A., Sohn, M., Kierdorf, H., Günther, R.W. Nephrol. Dial. Transplant. (1996) [Pubmed]
  29. Does the use of erythropoietin in hemodialysis patients increase dialysis graft thrombosis rates? Standage, B.A., Schuman, E.S., Ackerman, D., Gross, G.F., Ragsdale, J.W. Am. J. Surg. (1993) [Pubmed]
  30. Axillary-popliteal artery bypass provides successful limb salvage after removal of infected aortofemoral grafts. McCarthy, W.J., McGee, G.S., Lin, W.W., Pearce, W.H., Flinn, W.R., Yao, J.S. Archives of surgery (Chicago, Ill. : 1960) (1992) [Pubmed]
  31. Rheolytic catheter thrombectomy, balloon angioplasty, and direct recombinant tissue plasminogen activator thrombolysis of dural sinus thrombosis with preexisting hemorrhagic infarctions. Curtin, K.R., Shaibani, A., Resnick, S.A., Russell, E.J., Simuni, T. AJNR. American journal of neuroradiology. (2004) [Pubmed]
  32. Diagnostic and therapeutic strategies of white clot syndrome. AbuRahma, A.F., Boland, J.P., Witsberger, T. Am. J. Surg. (1991) [Pubmed]
  33. Current status of surgical therapy for deep vein thrombosis. Greenfield, L.J., Alexander, E.L. Am. J. Surg. (1985) [Pubmed]
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