Disease relevance of Akathisia, Drug-Induced

• Four subtypes of tardive dyskinesia could be distinguished: choreoathetosis, tardive dystonia, blepharospasm, and tardive akathisia [1].
• A distinction is usually made between classic tardive dyskinesia (TD) (orobuccal-lingual-facial) and tardive dystonia, tardive tremor (TT), tardive akathisia, and other related syndromes [2].

High impact information on Akathisia, Drug-Induced

• Lorazepam and anticholinergics in tardive akathisia [3].
• Propranolol in the treatment of tardive akathisia: a report of two cases [4].
• Tardive akathisia associated with low-dose haloperidol use [5].
• Pseudoakathisia associated with atenolol [6].
• Successful treatment of tardive akathisia with moclobemide, a reversible and selective monoamine-oxidase-A inhibitor. A case study [7].

Chemical compound and disease context of Akathisia, Drug-Induced

• The authors describe two cases of tardive akathisia following metoclopramide therapy, in which there were concomitant symptoms of agitated depression [8].
• Tardive akathisia due to sulpiride [9].
• Paroxetine and tardive akathisia [10].
• Fourteen patients with TD, all but one also having tardive akathisia, were evaluated on presynaptically acting dopamine-depleting drugs, reserpine, TBZ, and AMT [11].
• Treatment of tardive akathisia with clonidine [12].

Biological context of Akathisia, Drug-Induced

• One acute and one tardive akathisia patients, respectively, and 10 neuroleptic-treated schizophrenic patients were injected with biperiden 5 mg or saline and the response to anticholinergics was monitored by microvibration (MV) as an indicator of muscle tonus [13].

References