Disease relevance of Tooth Movement

• These results suggest that cyclic changes in the estradiol level may be associated with the estrous-cycle-dependent variation in tooth movement through its effects on bone resorption [1].
• The immediate palatal plate is therapeutically beneficial for relief of temporomandibular joint pain, for reduction of occlusal trauma with and without selective grinding, for orthodontic tooth movement as a disarticulating device, and for relief of pericementitis subsequent to periodontal surgery [2].

High impact information on Tooth Movement

• In this study, we examined the effect of mechanical loading on expression of DMP1 mRNA and DMP1 protein in alveolar bone in the mouse tooth movement model by in situ hybridization and immunocytochemistry [3].
• Effects of continuous infusion of PTH on experimental tooth movement in rats [4].
• Local RANKL gene transfer to the periodontal tissue accelerates orthodontic tooth movement [5].
• Local OPG gene transfer significantly diminished tooth movement [6].
• The in vivo levels of matrix metalloproteinase-1 and -8 in gingival crevicular fluid during initial orthodontic tooth movement [7].

Chemical compound and disease context of Tooth Movement

• Administration of imidazole and verapamil inhibited the appearance of osteoclasts and bone resorption induced by experimental tooth movement in rats [8].
• The aims of this study were: 1) to establish if Oc, Pyr and dPyr can be detected in GCF and 2) using the orthodontic tooth movement model of alveolar bone resorption to evaluate GCF levels of osteocalcin and these collagen cross-links as markers of bone breakdown [9].
• Effects of prostaglandin E2 on alveolar bone resorption during orthodontic tooth movement [10].
• Thus, 1,25-DHCC was found to be more effective in modulating bone turnover during orthodontic tooth movement, because its effects on bone formation and bone resorption were well balanced [11].

Biological context of Tooth Movement

• We tested whether orthodontic tooth movement (OTM) could be blocked by local administration of echistatin or an arginine-glycine-aspartic acid (RGD) peptide, agents known to perturb bone remodeling, adjacent to maxillary molars in rats [12].
• Serum estradiol levels also varied according to the estrous cycle, with a peak during pro-estrus and a nadir during estrus, and were inversely related to tooth movement [1].
• Therefore, SP may be involved in pulpal inflammation and root resorption during orthodontic tooth movement [13].
• Phenylephrine caused a temporal extrusive tooth movement and an increase in blood pressure at all doses [14].
• The aim of this study was to investigate compensatory lingual alveolar bone formation during tooth movement in young and old rats, using the vital bone marker tetracycline [15].

Anatomical context of Tooth Movement

• In the alveolar bone during experimental tooth movement, CTGF mRNA was expressed in osteoblasts and in osteocytes localized around the periodontal ligament under control conditions [16].
• ELVAX loaded with either RGD peptide or echistatin and surgically implanted next to the maxillary molars inhibited orthodontic tooth movement (p < 0.01) [12].
• We hypothesized that local OPG gene transfer to the periodontium would neutralize the RANKL activity induced by mechanical compressive force, thereby inhibiting osteoclastogenesis and diminishing tooth movement [6].
• Expression of Fos in the rat forebrain following experimental tooth movement [17].
• The purpose of this study was to examine the morphological changes in alveolar bone osteocytes on the pressure side during experimental tooth movement, using quantitative evaluation on hematoxylin and eosin-stained sections, the TUNEL method, confocal laser scanning microscopy (CLSM), and transmission electron microscopy [18].

Associations of Tooth Movement with chemical compounds

• Since high levels of prostaglandin (PG) E2 and interleukin (IL)-1 beta are found in the periodontal ligament (PDL) during tooth movement, and both factors are involved in the induction of pain, the effects of low-power laser irradiation on PGE2 and IL-1 beta production in stretched human PDL cells were studied in vitro [19].
• Fourteen days later, rats were subjected to lateral tooth movement in the upper molar with nickel-titanium wire of 10 g of force [20].
• This study shows the feasibility of using ELVAX to deliver integrin inhibitors adjacent to teeth to limit local tooth movement in response to orthodontic forces [12].
• Effects of echistatin and an RGD peptide on orthodontic tooth movement [12].
• These findings indicated that estrogen deficiency caused significantly rapid orthodontic tooth movement, and that the acceleration of tooth movement could be due to the further activation of alveolar bone turnover [20].

Gene context of Tooth Movement

• The aim of this study was to analyze effects of mechanical force during orthodontic tooth movement, in the pressure zone, on the induction of interferon-gamma (IFN-gamma) as a proinflammatory cytokine of Th1 type and interleukin-4 (IL-4)/IL-10 as anti-inflammatory cytokines of Th2 type [21].
• In this study, it was suggested that OPG and RANKL are involved in alveolar bone remodeling during orthodontic tooth movement [22].
• CONCLUSIONS: Our results suggest that human pulp fibroblasts may be involved in the progress of inflammation in pulp tissue during orthodontic tooth movement, as they produced large amounts of IL-1 beta, IL-6, and TNF-alpha following stimulation with neuropeptides [23].
• Growth hormone receptor and IGF-I receptor immunoreactivity during orthodontic tooth movement in the prednisolone-treated rat [24].
• Immediately after tooth movement, VIP-containing nerve fibers disappeared in the stretched part, and returned to the normal level after 14 days [25].

Analytical, diagnostic and therapeutic context of Tooth Movement

• Effects of topical administration of a bisphosphonate (risedronate) on orthodontic tooth movements in rats [26].
• Orthodontics. Part 11: orthodontic tooth movement [27].
• This study verified the effect of the association gypsum or silicone investment support materials and water immersion on the relative tooth movement in complete dentures [28].
• The tooth movements were recorded by a displacement detector under artificial respiration with halothane anaesthesia [29].
• This article considers the prevention of orthodontic problems, occlusal adjustments, simple tooth movements, rotational techniques, tipping problems, adjustment of crown height, descriptions of common orthodontic appliances, and problems associated with therapy [30].

References