Disease relevance of Pneumatosis Cystoides Intestinalis

• A patient with antinuclear antibody (ANA) negative systemic lupus erythematosus (SLE) developed pneumatosis cystoides intestinalis and spontaneous pneumoperitoneum [1].
• To the authors' knowledge, this is the first reported case of successful treatment of pneumatosis cystoides intestinalis with metronidazole in primary chronic intestinal pseudoobstruction [2].
• On day 57, the patient developed pneumatosis cystoides intestinalis (PCI) when she received cyclosporin A and corticosteroids for graft-versus-host disease (GVHD) [3].

High impact information on Pneumatosis Cystoides Intestinalis

• Pneumatosis cystoides intestinalis associated with autoantibodies against proliferating cell nuclear antigen: comment on the article by Nojima et al [4].
• Pneumatosis cystoides intestinalis and trichloroethylene exposure [5].
• Although the pathogenesis of pneumatosis cystoides intestinalis is not entirely clear, it seems likely that, in this case, mucosal ulceration secondary to methyl-gag allowed intraluminal air to dissect into the intestinal wall and surrounding retroperitoneal tissues [6].
• A case of pneumatosis cystoides intestinalis in the large bowel with complete resolution after eight weeks of metronidazole treatment is reported [7].
• Pneumatosis cystoides intestinalis. Nitrous oxide anaesthesia and the rapid effect of oxygen therapy [8].

Chemical compound and disease context of Pneumatosis Cystoides Intestinalis

• The association of increased colonic gas, secondary to fermentation of undigested lactose in the colon, and the reflux of the excessive gas into the excluded segment of small bowel and dissection of the gas into the bowel wall and mesentery are postulated as the causes of pneumatosis cystoides intestinalis in patients with jejunoileal bypass [9].
• Pneumatosis cystoides intestinalis: an unexpected finding in intestinal bleeding under therapy with phenprocoumon [10].
• Pneumatosis cystoides intestinalis has been detected in 3/103 kidney transplant patients (3%) treated with CsA and prednisone, in contrast to less than 1% of kidney transplant patients treated with Aza and prednisone [11].
• This led to more serious complications, malabsorption, pneumoperitoneum, and pneumatosis cystoides intestinalis, which forced a decision to treat her with home total parenteral nutrition [12].

References