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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Gastric Stump

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Disease relevance of Gastric Stump


High impact information on Gastric Stump

  • Enhanced induction by high-cholesterol diet of remnant gastric carcinogenesis by N-methyl-N'-nitro-N-nitrosoguanidine in rats [5].
  • In contrast with the poor prognosis of patients with cancers of the gastric remnant of tumour stages T2 to T4 according to the TNM-classification regardless of their NM-stage, patients with tumour stage T1N0 and T1N1 have a good prognosis [6].
  • These results suggest that compensatory ghrelin production can occur in the remnant stomach after the surgical removal of part of the stomach and that the proximal fundus is more important than the distal antrum and body in terms of the capacity for ghrelin production [7].
  • In noncancerous mucosa of the remnant stomach in the RB group, RUNX3 expression decreased more near the anastomosis area [8].
  • CONCLUSION: Bacterial culture had the highest diagnostic value in the remnant stomach as well as unoperated stomach [9].

Chemical compound and disease context of Gastric Stump


Biological context of Gastric Stump


Anatomical context of Gastric Stump


Associations of Gastric Stump with chemical compounds


Gene context of Gastric Stump

  • CONCLUSIONS: This information may help in the analysis of the carcinogenesis of gastric cancer; there is also a possibility that the COX-2 selective inhibitor to the remnant gastric cancer has a chemopreventive effect [20].
  • N-Nitroso compounds, bacteria, and carcinoembryonic antigen in the gastric stump [21].
  • (a) The ODC activity was significantly higher in the stomal portion [455 +/- 340 (mean +/- SD)] of the gastric remnant than in the greater curvature (148 +/- 107) [17].
  • To detect protein expression, immunohistochemical staining was employed. p16 promoter hypermethylation was observed more often in remnant gastric cancer than in PC [22].
  • Risk analysis of carcinogenesis in the remnant stomach with measurement of ornithine decarboxylase activity [23].

Analytical, diagnostic and therapeutic context of Gastric Stump


  1. Pathological features and mucin histochemistry of primary gastric stump carcinoma associated with gastritis cystica polyposa. A study of six cases. Bogomoletz, W.V., Potet, F., Barge, J., Molas, G., Qizilbash, A.H. Am. J. Surg. Pathol. (1985) [Pubmed]
  2. Bile acids promote carcinogenesis in the remnant stomach of rats. Kuwahara, A., Saito, T., Kobayashi, M. J. Cancer Res. Clin. Oncol. (1989) [Pubmed]
  3. Helicobacter pylori may survive ampicillin treatment in the remnant stomach. Hosaka, Y., Okamoto, R., Irinoda, K., Kaieda, S., Koizumi, W., Saigenji, K., Inoue, M. J. Antibiot. (2002) [Pubmed]
  4. Helicobacter pylori and Epstein-Barr virus infection and the p53 tumour suppressor pathway in gastric stump cancer compared with carcinoma in the non-operated stomach. Baas, I.O., van Rees, B.P., Musler, A., Craanen, M.E., Tytgat, G.N., van den Berg, F.M., Offerhaus, G.J. J. Clin. Pathol. (1998) [Pubmed]
  5. Enhanced induction by high-cholesterol diet of remnant gastric carcinogenesis by N-methyl-N'-nitro-N-nitrosoguanidine in rats. Makino, M., Kaibara, N., Koga, S. J. Natl. Cancer Inst. (1989) [Pubmed]
  6. Early cancer of the gastric remnant. Pointner, R., Schwab, G., Königsrainer, A., Bodner, E., Schmid, K.W. Gut (1988) [Pubmed]
  7. Changes in plasma ghrelin concentration immediately after gastrectomy in patients with early gastric cancer. Jeon, T.Y., Lee, S., Kim, H.H., Kim, Y.J., Son, H.C., Kim, D.H., Sim, M.S. J. Clin. Endocrinol. Metab. (2004) [Pubmed]
  8. Frequent loss of RUNX3 gene expression in remnant stomach cancer and adjacent mucosa with special reference to topography. Nakase, Y., Sakakura, C., Miyagawa, K., Kin, S., Fukuda, K., Yanagisawa, A., Koide, K., Morofuji, N., Hosokawa, Y., Shimomura, K., Katsura, K., Hagiwara, A., Yamagishi, H., Ito, K., Ito, Y. Br. J. Cancer (2005) [Pubmed]
  9. Diagnostic value of culture, histology and PCR for Helicobacter pylori in the remnant stomach after surgery. Matsukura, N., Tajiri, T., Kato, S., Togashi, A., Masuda, G., Tokunaga, A., Yamada, N. Aliment. Pharmacol. Ther. (2004) [Pubmed]
  10. Helicobacter pylori of remnant stomach and optimal dose of amoxicillin for eradicating Helicobacter pylori. Rino, Y., Imada, T., Shiozawa, M., Saeki, H., Kabara, T., Tanaka, J., Amano, T., Kondo, J. Hepatogastroenterology (2000) [Pubmed]
  11. Gastric emptying and clinical outcome after Roux-en-Y diversion. Britton, J.P., Johnston, D., Ward, D.C., Axon, A.T., Barker, M.C. The British journal of surgery. (1987) [Pubmed]
  12. Flow cytometric analysis of the DNA content of tumor cells in cases of gastric cancer in the upper third of the stomach and in the remnant stomach. Ikeguchi, M., Kondou, A., Oka, A., Tsujitani, S., Maeta, M., Kaibara, N. Oncology (1995) [Pubmed]
  13. Malignant lymphoma occurring in the residual stomach following gastrectomy: plus discussion based on the literature in Japan. Oshita, H., Tanemura, H., Kanno, A., Kusakabe, M., Hato, T., Tomita, E., Yamada, T. Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association. (2003) [Pubmed]
  14. Gastrin production following antrectomy. A study on the occurrence of gastrin-producing cells and the serum gastrin response to feeding. Nielsen, H.O., Lauritsen, K., Hansen, M.G., Christiansen, L.A. Acta pathologica, microbiologica, et immunologica Scandinavica. Section A, Pathology. (1983) [Pubmed]
  15. Effectiveness of Roux-en-Y reconstruction after distal gastrectomy based on an assessment of biliary kinetics. Shinoto, K., Ochiai, T., Suzuki, T., Okazumi, S., Ozaki, M. Surgery today. (2003) [Pubmed]
  16. Incidence of bile reflux in gastric ulcer and after partial gastrectomy. Poxon, V., Hogg, B., Youngs, D., Morris, D.L., Keighley, M.R. The British journal of surgery. (1986) [Pubmed]
  17. Ornithine decarboxylase activity in the mucosa of gastric remnant following gastric surgery. Nakanishi, I., Sowa, M., Otani, S. Cancer Epidemiol. Biomarkers Prev. (1993) [Pubmed]
  18. A comparison of regional versus systemic drug injection. Adriamycin concentration in peripheral blood and gastric stump (post-Billroth II gastrectomy) in the dog. P'eng, F.K., Wu, C.W., Chang, T.J., Lui, W.Y. Cancer Chemother. Pharmacol. (1989) [Pubmed]
  19. Acute intracranial hypertension-induced inhibition of gastric emptying: evaluation in conscious rats. Kacker, V., Mehta, V.S., Gupta, Y.K. Eur. J. Pharmacol. (1999) [Pubmed]
  20. Expression of cyclooxygenase-2 in primary and remnant gastric carcinoma: comparing it with p53 accumulation, Helicobacter pylori infection, and vascular endothelial growth factor expression. Kawabe, A., Shimada, Y., Uchida, S., Maeda, M., Yamasaki, S., Kato, M., Hashimoto, Y., Ohshio, G., Matsumoto, M., Imamura, M. Journal of surgical oncology. (2002) [Pubmed]
  21. N-Nitroso compounds, bacteria, and carcinoembryonic antigen in the gastric stump. Guadagni, S., Pistoia, M.A., Valenti, M., Leocata, P., Coletti, G., Calvisi, G., Madonna, R., Deraco, M., Reed, P.I. J. Surg. Res. (1998) [Pubmed]
  22. Frequent p16 CpG island hypermethylation in primary remnant gastric cancer suggesting an independent carcinogenic pathway. Mino, A., Onoda, N., Yashiro, M., Aya, M., Fujiwara, I., Kubo, N., Sawada, T., Ohira, M., Kato, Y., Hirakawa, K. Oncol. Rep. (2006) [Pubmed]
  23. Risk analysis of carcinogenesis in the remnant stomach with measurement of ornithine decarboxylase activity. Kitao, Y., Yamane, T., Kikuoka, N., Matsumoto, H., Oya, K., Inagake, M., Takahashi, T. Journal of surgical oncology. (1994) [Pubmed]
  24. Promoting effect of partial gastrectomy on carcinogenesis in the remnant stomach of rats after oral administration of N-methyl-N'-nitro-N-nitrosoguanidine. Sano, C., Kumashiro, R., Saito, T., Inokuchi, K. Oncology (1984) [Pubmed]
  25. High prevalence of Epstein-Barr virus in gastric remnant carcinoma after Billroth-II reconstruction. Nishikawa, J., Yanai, H., Hirano, A., Okamoto, T., Nakamura, H., Matsusaki, K., Kawano, T., Miura, O., Okita, K. Scand. J. Gastroenterol. (2002) [Pubmed]
  26. Quantitative determinations of duodenogastric reflux, prevalence of Helicobacter pylori infection, and concentrations of interleukin-8. Fukuhara, K., Osugi, H., Takada, N., Takemura, M., Ohmoto, Y., Kinoshita, H. World journal of surgery. (2003) [Pubmed]
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