Disease relevance of Isosporiasis

• By survival analysis, diarrhea from isosporiasis and cyclosporiasis ceased more rapidly with trimethoprim-sulfamethoxazole than with ciprofloxacin [1].

High impact information on Isosporiasis

• We conclude that isosporiasis in patients with AIDS can be treated effectively with a 10-day course of trimethoprim-sulfamethoxazole and that recurrent disease can subsequently be prevented by ongoing prophylaxis with either trimethoprim-sulfamethoxazole or sulfadoxine-pyrimethamine [2].
• Treatment of isosporiasis with combined albendazole and ornidazole in patients with AIDS [3].
• Use of diclazuril for the treatment of isosporiasis in patients with AIDS [4].
• Case report: Nitazoxanide treatment failure in chronic isosporiasis [5].
• We report a 60-year-old immunocompetent patient with chronic biliary isosporiasis who failed to respond to orally administered cotrimoxazole prophylaxis and orally administered treatment with nitazoxanide, a 5-nitrothiazole benzamide compound [5].

Chemical compound and disease context of Isosporiasis

• In all patients with isosporiasis, diarrhea stopped within two days of the beginning of treatment with oral trimethoprim-sulfamethoxazole [6].
• Recurrent isosporiasis over a decade in an immunocompetent host successfully treated with pyrimethamine [7].
• It was refractory to treatment with dihydrofolate reductase inhibitor combined with sulfonamide such as cotrimoxazole to which isosporiasis usually responds well and is being described here for clinical interest and uniqueness of its presentation and laboratory findings [8].

Analytical, diagnostic and therapeutic context of Isosporiasis

• Later she developed recurrent isosporiasis after chemotherapy for the underlying disease, but institution of co-trimoxazole again resolved the symptoms [9].

References