Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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MeSH Review:

Drug Resistance, Viral

Jacobson, M.A., Locarnini, S. et al.

Locarnini, Hatzakis, Heathcote, Keeffe, Liang, Mutimer, Pawlotsky, Zoulim,

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High impact information on Drug Resistance, Viral

Confirmation of antiviral drug failure can be established by sequencing the HBV DNA polymerase and identifying specific genetic markers of antiviral drug resistance [1].
Preliminary data from a placebo-controlled trial of oral ganciclovir suggest that this agent reduces the risk of developing CMV end-organ disease by 50%; however, the implications of oral ganciclovir prophylaxis for development of antiviral drug resistance are unknown [2].

References

Management of antiviral resistance in patients with chronic hepatitis B. Locarnini, S., Hatzakis, A., Heathcote, J., Keeffe, E.B., Liang, T.J., Mutimer, D., Pawlotsky, J.M., Zoulim, F. Antivir. Ther. (Lond.) (2004) [Pubmed]
Update (1995) on clinical trials of antiviral therapy and prophylaxis for AIDS-related cytomegalovirus disease. Jacobson, M.A. Scandinavian journal of infectious diseases. Supplementum. (1995) [Pubmed]

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