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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
MeSH Review

Verbenaceae

 
 
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Disease relevance of Verbenaceae

 

High impact information on Verbenaceae

  • [structure: see text] An unusual iridoid glucoside, namely 9-hydroxy-8-epihastatoside (1), was isolated from Junellia seriphioides (Verbenaceae), together with the known compounds auroside (2), pulchelloside I (3), and 8-epihastatoside (4) as well as verbascoside [2].
  • The 70% aqueous methanol extract of the Peruvian plant Lippia alva (Verbenaceae) was found to contain three novel compounds, 1, 2, and 3, which were identified as inhibitors of the chemokine receptor CCR5 [3].
  • (Viticis Fructus; Verbenaceae) along with three known diterpenes, rotundifuran, dihydrosolidagenone and abietatriene 3beta-ol [4].
  • Seven new clerodane-type diterpenoids, named peronemins B2 (1), A2 (2), B1 (3), C1 (4), B3 (5), A3 (6), and D1 (7), were isolated from the leaves of Peronema canescens (Verbenaceae), an Indonesian medicinal plant collected in Bengkulu, Sumatera Island, Indonesia [5].
  • In the present work, the anti-inflammatory and gastroprotective properties of ethanolic extracts of Stachytarpheta cayennesis (L.C. Rich) Vahl (Verbenaceae) were assessed [6].
 

Chemical compound and disease context of Verbenaceae

 

Biological context of Verbenaceae

 

Associations of Verbenaceae with chemical compounds

  • Assessment of the protective potential of Premna tomentosa (L. Verbenaceae) extract on lipid profile and lipid-metabolizing enzymes in acetaminophen-intoxicated rats [9].
  • (Verbenaceae) is the source of hernandulcin, the first known intensely sweet sesquiterpenoid, a compound which is a volatile oil constituent [10].
  • Based on our results, we can say that as a general rule the ethanol extracts of plants belonging to the Verbenaceae family showed lower EC(50) values than the other plant extracts [11].
  • (Verbenaceae) showed radicalscavenging activity in the 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay [12].
  • The effect of Premna integrifolia Linn. (Verbenaceae) on blood glucose in streptozotocin induced type 1 and type 2 diabetic rats [13].
 

Gene context of Verbenaceae

  • The alcoholic and n-butanolic extracts of dried leaves of Stachytarpheta cayennensis (L.C. Rich) Vahl (Verbenaceae) was assessed in antiinflammatory and antinociceptive models [14].

References

  1. In vitro antiviral effect of flavonoid-rich extracts of Vitex polygama (Verbenaceae) against acyclovir-resistant herpes simplex virus type 1. Gonçalves, J.L., Leitão, S.G., Monache, F.D., Miranda, M.M., Santos, M.G., Romanos, M.T., Wigg, M.D. Phytomedicine (2001) [Pubmed]
  2. A 9-hydroxyiridoid isolated from Junellia seriphioides (Verbenaceae). Franzyk, H., Jensen, S.R., Olsen, C.E., Quiroga, J.M. Org. Lett. (2000) [Pubmed]
  3. Three new compounds from the plant Lippia alva as inhibitors of chemokine receptor 5 (CCR5). Hegde, V.R., Pu, H., Patel, M., Das, P.R., Strizki, J., Gullo, V.P., Chou, C.C., Buevich, A.V., Chan, T.M. Bioorg. Med. Chem. Lett. (2004) [Pubmed]
  4. Diterpenoids from the fruits of Vitex trifolia. Ono, M., Sawamura, H., Ito, Y., Mizuki, K., Nohara, T. Phytochemistry (2000) [Pubmed]
  5. Indonesian medicinal plants. VII. Seven new clerodane-type diterpenoids, peronemins A2, A3, B1, B2, B3, C1, and D1, from the leaves of Peronema canescens (Verbenaceae). Kitagawa, I., Simanjuntak, P., Hori, K., Nagami, N., Mahmud, T., Shibuya, H., Kobayashi, M. Chem. Pharm. Bull. (1994) [Pubmed]
  6. Anti-inflammatory and anti-ulcerogenic properties of Stachytarpheta cayennensis (L.C. Rich) Vahl. Penido, C., Costa, K.A., Futuro, D.O., Paiva, S.R., Kaplan, M.A., Figueiredo, M.R., Henriques, M.G. Journal of ethnopharmacology. (2006) [Pubmed]
  7. Zinc iodide-osmium tetroxide (ZIO) reactive sites in the extrafloral nectary of Citharexylum mirianthum Cham. (Verbenaceae). Machado, S.R., Gregório, E.A. Tissue & cell. (2001) [Pubmed]
  8. Anti-inflammatory activity and lipid peroxidation inhibition of iridoid lamiide isolated from Bouchea fluminensis (Vell.) Mold. (Verbenaceae). Delaporte, R.H., Sánchez, G.M., Cuellar, A.C., Giuliani, A., Palazzo de Mello, J.C. Journal of ethnopharmacology. (2002) [Pubmed]
  9. Assessment of the protective potential of Premna tomentosa (L. Verbenaceae) extract on lipid profile and lipid-metabolizing enzymes in acetaminophen-intoxicated rats. Devi, K.P., Sreepriya, M., Balakrishna, K., Veluchamy, G., Devaki, T. Journal of alternative and complementary medicine (New York, N.Y.) (2004) [Pubmed]
  10. The intensely sweet herb, Lippia dulcis Trev.: historical uses, field inquiries, and constituents. Compadre, C.M., Robbins, E.F., Kinghorn, A.D. Journal of ethnopharmacology. (1986) [Pubmed]
  11. Screening of Brazilian plant extracts for antioxidant activity by the use of DPPH free radical method. Mensor, L.L., Menezes, F.S., Leitão, G.G., Reis, A.S., dos Santos, T.C., Coube, C.S., Leitão, S.G. Phytotherapy research : PTR. (2001) [Pubmed]
  12. Phytochemical investigation and antioxidant activity of Duranta repens. Shahat, A.A., Nazif, N.M., Abousetta, L.M., Ibrahim, N.A., Cos, P., Van Miert, S., Pieters, L., Vlietinck, A.J. Phytotherapy research : PTR. (2005) [Pubmed]
  13. The effect of Premna integrifolia Linn. (Verbenaceae) on blood glucose in streptozotocin induced type 1 and type 2 diabetic rats. Alamgir, M., Rokeya, B., Hannan, J.M., Choudhuri, M.S. Die Pharmazie. (2001) [Pubmed]
  14. Antiinflammatory and antinociceptive activities of extracts and isolated compounds from Stachytarpheta cayennensis. Schapoval, E.E., Vargas, M.R., Chaves, C.G., Bridi, R., Zuanazzi, J.A., Henriques, A.T. Journal of ethnopharmacology. (1998) [Pubmed]
 
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