Disease relevance of Sapindus

• The effect of the aqueous extract of Sapindus trifoliatus (ST) on chemical, thermal-induced pain, nitroglycerin-induced hyperalgesia and pain on inflamed tissue was investigated [1].
• The studies indicate that Sapindus saponins as compared to nonoxynol-9 are far less toxic to lactobacillus species and therefore saponins containing spermicidal preparations are likely to be more vaginal-friendly than equivalent nonoxynol-9 preparations [2].

High impact information on Sapindus

• Triglyceride composition of Sapindus mukorossi seed oil [3].
• The fatty acid composition of Sapindus mukorossi seed oil was determined by spectrophotometry, urea complexation, and gas liquid chromatography (GLC) [3].
• The special characteristic of the Sapindus mukorossi seed oil is its content of 26.3 and 26.7% triolein and eicoseno-di-oleins, respectively [3].
• Under identical conditions four similar reactors were operated in parallel with the following additives: control with no additive, anionic part of Reetha (Sapindus trifoliata) extract, cationic part of Reetha extract, and Chitosan [4].
• New dammarane-type saponins from the galls of Sapindus mukorossi [5].

Anatomical context of Sapindus

• The aqueous extract of pericarp of fruits of Sapindus trifoliatus Linn (ST), family Sapindaceae was evaluated for its affinity for 5-HT(1B/1D) receptors in rabbit saphenous vein, alpha-adrenoceptors in rabbit aorta, GABA receptors in guinea pig ileum, 5-HT(2B) receptors in rat fundus and vanilloid receptors in guinea pig trachea [6].

Associations of Sapindus with chemical compounds

• Anti-inflammatory activities of hederagenin and crude saponin isolated from Sapindus mukorossi Gaertn [7].
• One of the monodesmosides was identified as sapindoside A, previously isolated from Sapindus spp [8].
• From the pericarps of Sapindus emarginatus (Sapindaceae), three new acetylated triterpene saponins were isolated together with hederagenin and five known triterpene saponins, as well as one known sweet acyclic sesquiterpene glycoside, mukurozioside IIb [9].
• New tirucallane-type triterpenoid saponins from Sapindus mukorossi Gaetn [10].
• The aqueous extract of Sapindus trifoliatus exhibited significant 5-HT(2B) receptor inhibition and moderate platelet serotonin release inhibition [6].

References