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MeSH Review:

Scolymus

Emendörfer, F. et al., Kirimer, N. et al., López-Molina, D. et al., Gebhardt, R., Llorente, B.E. et al.

Llorente, Brutti, Caffini,

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High impact information on Scolymus

Inhibition of cholesterol biosynthesis in primary cultured rat hepatocytes by artichoke (Cynara scolymus L.) extracts [1].
Antispasmodic and spasmogenic effects of Scolymus hispanicus and taraxasteryl acetate on isolated ileum preparations [2].
Taraxasteryl acetate (1) was identified as the major triterpenoid of the ethanolic extract of the root bark of Scolymus hispanicus L [2].
Purification and characterization of a milk-clotting aspartic proteinase from globe artichoke (Cynara scolymus L.) [3].
A basic heme peroxidase isoenzyme (AKPC) has been purified to homogeneity from artichoke flowers (Cynara scolymus L.). The enzyme was shown to be a monomeric glycoprotein, M(r)=42300+/-1000, (mean+/-S.D.) with an isoelectric point >9 [4].

Associations of Scolymus with chemical compounds

On the other hand, ME from Calophyllum brasiliense and Cynara scolymus exhibited significant inhibitory activity for the contractile response elicited by acetylcholine on guinea-pig ileum and on rat duodenum in a noncompetitive and concentration-dependent manner [5].

References

Inhibition of cholesterol biosynthesis in primary cultured rat hepatocytes by artichoke (Cynara scolymus L.) extracts. Gebhardt, R. J. Pharmacol. Exp. Ther. (1998) [Pubmed]
Antispasmodic and spasmogenic effects of Scolymus hispanicus and taraxasteryl acetate on isolated ileum preparations. Kirimer, N., Tunalier, Z., Başer, K.H., Cingi, I. Planta Med. (1997) [Pubmed]
Purification and characterization of a milk-clotting aspartic proteinase from globe artichoke (Cynara scolymus L.). Llorente, B.E., Brutti, C.B., Caffini, N.O. J. Agric. Food Chem. (2004) [Pubmed]
Purification and characterization of a new cationic peroxidase from fresh flowers of Cynara scolymus L. López-Molina, D., Heering, H.A., Smulevich, G., Tudela, J., Thorneley, R.N., García-Cánovas, F., Rodríguez-López, J.N. J. Inorg. Biochem. (2003) [Pubmed]
Evaluation of the relaxant action of some Brazilian medicinal plants in isolated guinea-pig ileum and rat duodenum. Emendörfer, F., Emendörfer, F., Bellato, F., Noldin, V.F., Niero, R., Cechinel-Filho, V., Cardozo, A.M. Journal of pharmacy & pharmaceutical sciences [electronic resource] : a publication of the Canadian Society for Pharmaceutical Sciences, Société canadienne des sciences pharmaceutiques. (2005) [Pubmed]

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