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MeSH Review


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Disease relevance of Pterocarpus


High impact information on Pterocarpus


Chemical compound and disease context of Pterocarpus


Biological context of Pterocarpus


Anatomical context of Pterocarpus


Associations of Pterocarpus with chemical compounds


Gene context of Pterocarpus

  • In conclusion, this is the first study to describe the selective COX-2 inhibitory activity of a Pterocarpus marsupium extract [4].
  • Therefore, we postulate that the isoflavone from Pterocarpus marsupium may activate glucose transport by a PI3 kinase independent pathway, which require further analysis [7].
  • The inhibitory effect of cycloheximide on Pterocarpus marsupium methanolic extract and Pterocarpus marsupium isoflavone-mediated glucose uptake suggested that new protein synthesis is required for elevated Glut-4 protein expression [7].
  • (-)Epicatechin, an active principle in the water extract of the bark of Pterocarpus marsupium increases the cAMP content of the islets which is associated with the increased insulin release, conversion of proinsulin to insulin and cathepsin B activity [13].

Analytical, diagnostic and therapeutic context of Pterocarpus


  1. A constituent of Pterocarpus marsupium, (-)-epicatechin, as a potential antidiabetic agent. Sheehan, E.W., Zemaitis, M.A., Slatkin, D.J., Schiff, P.L. J. Nat. Prod. (1983) [Pubmed]
  2. Traditional Indian systems of medicine. Lodha, R., Bagga, A. Ann. Acad. Med. Singap. (2000) [Pubmed]
  3. Crystal structure of Pterocarpus angolensis lectin in complex with glucose, sucrose, and turanose. Loris, R., Imberty, A., Beeckmans, S., Van Driessche, E., Read, J.S., Bouckaert, J., De Greve, H., Buts, L., Wyns, L. J. Biol. Chem. (2003) [Pubmed]
  4. Selective COX-2 inhibition by a Pterocarpus marsupium extract characterized by pterostilbene, and its activity in healthy human volunteers. Hougee, S., Faber, J., Sanders, A., de Jong, R.B., van den Berg, W.B., Garssen, J., Hoijer, M.A., Smit, H.F. Planta Med. (2005) [Pubmed]
  5. Crystallization and crystal manipulation of the Pterocarpus angolensis seed lectin. Loris, R., Garcia-Pino, A., Buts, L., Bouckaert, J., Beeckmans, S., De Greve, H., Wyns, L. Acta Crystallogr. D Biol. Crystallogr. (2005) [Pubmed]
  6. Antihyperglycemic activity of phenolics from Pterocarpus marsupium. Manickam, M., Ramanathan, M., Jahromi, M.A., Chansouria, J.P., Ray, A.B. J. Nat. Prod. (1997) [Pubmed]
  7. Upregulation of Glut-4 and PPAR gamma by an isoflavone from Pterocarpus marsupium on L6 myotubes: a possible mechanism of action. Anandharajan, R., Pathmanathan, K., Shankernarayanan, N.P., Vishwakarma, R.A., Balakrishnan, A. Journal of ethnopharmacology. (2005) [Pubmed]
  8. Savinin, a lignan from Pterocarpus santalinus inhibits tumor necrosis factor-alpha production and T cell proliferation. Cho, J.Y., Park, J., Kim, P.S., Yoo, E.S., Baik, K.U., Park, M.H. Biol. Pharm. Bull. (2001) [Pubmed]
  9. An isoflavone from Pterocarpus santalinus. Krishnaveni, K.S., Rao, J.V. Phytochemistry (2000) [Pubmed]
  10. Two aurone glycosides from heartwood of Pterocarpus santalinus. Kesari, A.N., Gupta, R.K., Watal, G. Phytochemistry (2004) [Pubmed]
  11. alpha-Glucosidase inhibitory activity of some Sri Lanka plant extracts, one of which, Cassia auriculata, exerts a strong antihyperglycemic effect in rats comparable to the therapeutic drug acarbose. Abesundara, K.J., Matsui, T., Matsumoto, K. J. Agric. Food Chem. (2004) [Pubmed]
  12. Effect of aqueous extract of Pterocarpus marsupium wood on alloxan-induced diabetic rats. Mukhtar, H.M., Ansari, S.H., Ali, M., Bhat, Z.A., Naved, T. Die Pharmazie. (2005) [Pubmed]
  13. Effect of (-)epicatechin on cAMP content, insulin release and conversion of proinsulin to insulin in immature and mature rat islets in vitro. Ahmad, F., Khan, M.M., Rastogi, A.K., Chaubey, M., Kidwai, J.R. Indian J. Exp. Biol. (1991) [Pubmed]
  14. Effect of oral administration of bark extracts of Pterocarpus santalinus L. on blood glucose level in experimental animals. Kameswara Rao, B., Giri, R., Kesavulu, M.M., Apparao, C. Journal of ethnopharmacology. (2001) [Pubmed]
  15. Antimicrobial terpenoids from Pterocarpus indicus. Ragasa, C.Y., De Luna, R.D., Hofilena, J.G. Nat. Prod. Res. (2005) [Pubmed]
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