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MeSH Review

Overnutrition

 
 
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Disease relevance of Overnutrition

 

Psychiatry related information on Overnutrition

 

High impact information on Overnutrition

 

Chemical compound and disease context of Overnutrition

  • Mothers who have had gestations diabetes (latent diabetics-LD), as well as those who have produced a large-for-dates baby (LFD) but who were not known to have been diabetic, have raised fasting plasma glucose levels, and these may induce fetal overnutrition [11].
  • Overnutrition may increase CO2 production and increase ventilatory demands [12].
  • As the Select Committee continued its work, problems of overnutrition became more apparent [13].
  • Moreover, the size of fat depots and the increase of brush-border-bound AP activity in MSG rats belonging to the SL and NL groups was quantitatively similar to the values size of these parameters observed in SL obese rats subjected to early postnatal overnutrition [14].
  • The influence of early postnatal overnutrition on peripheric thyroxine metabolism in rats [15].
 

Biological context of Overnutrition

 

Anatomical context of Overnutrition

 

Gene context of Overnutrition

  • The GHBP/receptor level is nutritionally regulated, with levels low in undernutrition and high in overnutrition [18].
  • Perhaps leptin, through increased insulin secretion, might induce GHBP/GH secretion, explaining the normal to high insulin-like growth factor (IGF)-I levels found in overnutrition [19].
  • Overnutrition induced a decrease in glucose storage at the low and high insulin concentrations: 1.2 +/- 0.3 to 0.2 +/- 0.3, P less than 0.01, and 6.4 +/- 0.3 to 4.3 +/- 0.5, mg/kg FFM min, P less than 0.001 [20].
  • Accordingly, one can question whether its sensitivity to nutritional supply could be used in healthy populations for the discrimination of groups with low or high energy intakes; if such were the case, could TBPA serve as an index of overnutrition [21]?

References

  1. Gastric inhibitory polypeptide links overnutrition to obesity. Ballinger, A. Gut (2003) [Pubmed]
  2. Malnutrition in institutionalized elderly: how and why? Keller, H.H. Journal of the American Geriatrics Society. (1993) [Pubmed]
  3. Serum cholesterol in cross-cultural perspective. The Seven Countries Study. Kromhout, D. Acta cardiologica. (1999) [Pubmed]
  4. Nutrition related hormonal changes in obese children. Yasunaga, T., Furukawa, S., Katsumata, N., Horikawa, R., Tanaka, T., Tanae, A., Hibi, I. Endocr. J. (1998) [Pubmed]
  5. Dyslipoproteinemia and other risk factors for atherosclerosis in children and adolescents. Kwiterovich, P.O. Atherosclerosis (1994) [Pubmed]
  6. Dietary-induced alterations in thyroid hormone metabolism during overnutrition. Danforth, E., Horton, E.S., O'Connell, M., Sims, E.A., Burger, A.G., Ingbar, S.H., Braverman, L., Vagenakis, A.G. J. Clin. Invest. (1979) [Pubmed]
  7. Immune response in overnutrition. Chandra, R.K. Cancer Res. (1981) [Pubmed]
  8. Malonyl-CoA signaling, lipid partitioning, and glucolipotoxicity: role in beta-cell adaptation and failure in the etiology of diabetes. Prentki, M., Joly, E., El-Assaad, W., Roduit, R. Diabetes (2002) [Pubmed]
  9. Lipotoxicity of beta-cells in obesity and in other causes of fatty acid spillover. Unger, R.H., Zhou, Y.T. Diabetes (2001) [Pubmed]
  10. Mechanisms of nutrient modulation of the immune response. Cunningham-Rundles, S., McNeeley, D.F., Moon, A. J. Allergy Clin. Immunol. (2005) [Pubmed]
  11. Relation of fasting plasma glucose concentration to plasma insulin and glucagon concentrations. Studies in latent diabetics and women who have produced large-for-dates babies. Turner, R.C., Harris, E., Bloom, S.R., Uren, C. Diabetes (1977) [Pubmed]
  12. A sensible approach to the nutritional support of mechanically ventilated critically ill patients. Christman, J.W., McCain, R.W. Intensive care medicine. (1993) [Pubmed]
  13. Nutrition policy--from neglect and uncertainty to debate and action. Lee, P.R. Journal of the American Dietetic Association. (1978) [Pubmed]
  14. Obesity and changes of alkaline phosphatase activity in the small intestine of 40- and 80-day-old rats subjected to early postnatal overfeeding or monosodium glutamate. Mozes, S., Sefcíková, Z., Lenhardt, L., Racek, L. Physiological research / Academia Scientiarum Bohemoslovaca. (2004) [Pubmed]
  15. The influence of early postnatal overnutrition on peripheric thyroxine metabolism in rats. Aust, L., Hartmann, K., Weber, A., Noack, R., Proll, J. Exp. Clin. Endocrinol. (1986) [Pubmed]
  16. Age-period-cohort analysis of breast cancer mortality. Chie, W.C., Chen, C.F., Lee, W.C., Chen, C.J., Lin, R.S. Anticancer Res. (1995) [Pubmed]
  17. Physiology of GIP--a lesson from GIP receptor knockout mice. Yamada, Y., Seino, Y. Horm. Metab. Res. (2004) [Pubmed]
  18. Growth hormone-binding proteins in plasma. Baumann, G., Mercado, M. Nutrition (Burbank, Los Angeles County, Calif.) (1993) [Pubmed]
  19. Insulin sensitivity and secretion influence the relationship between growth hormone-binding-protein and leptin. Fernandez-Real, J.M., Granada, M.L., Ruzafa, A., Casamitjana, R., Ricart, W. Clin. Endocrinol. (Oxf) (2000) [Pubmed]
  20. Overnutrition induced decrease in insulin action for glucose storage: in vivo and in vitro in man. Mott, D.M., Lillioja, S., Bogardus, C. Metab. Clin. Exp. (1986) [Pubmed]
  21. Thyroxine-binding prealbumin, overnutrition and apolipoprotein A1. Chavance, M., Labarre, C., Bleiberg, F., Jacqueson, A., Ducimetiere, P., Lemonnier, D., Wade, S. Human nutrition. Clinical nutrition. (1986) [Pubmed]
 
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