High impact information on Tissue and Organ Harvesting

• The univariate analysis demonstrated that CCL2/MCP-1 release was significantly associated with the surgical team in charge for organ harvesting, the proteins for dilution solution, the type of gradient, the type of enzyme, and the donor noradrenalin treatment [1].
• METHODS: Twelve-month-old Fischer 344 donor rats either were treated with prednisolone, mycophenolate mofetil, RAD, or FK506 24 hr and 1 hr before organ harvesting or remained untreated [2].
• Denervation of the liver before organ harvesting or treatment with hexamethonium prevented the effects of organ manipulation on all parameters studied [3].
• After organ harvesting, the rate of entry and exit of fluorescein dextran, a dye confined to the vascular space, was decreased 2- to 4-fold, and the maximal increase of surface fluorescence was blunted about 2-fold [3].
• Circulation-arrested cadaver lungs ventilated with 100% O2 prior to organ retrieval have superior pulmonary function after transplant compared with lungs ventilated with AG [4].

Anatomical context of Tissue and Organ Harvesting

• During cadaveric organ harvesting removal of the right renal vein and a segment of the vena cava may facilitate venous anastomosis of the right kidney [5].

Associations of Tissue and Organ Harvesting with chemical compounds

• One twin received betamethasone (10 microg/h iv) while the second twin received vehicle (0.9% NaCl) for 48 h immediately before the final physiological measurements and tissue harvesting [6].
• One group of pigs was fed idebenone (280 mg/day/7days) prior to organ harvesting [7].
• In a prospective double-blind trial, 127 kidneys were randomised to receive Eurocollins (n = 65) or Eurocollins plus nicardipine (n = 62) as a second flush solution at the time of organ retrieval [8].
• The use of donor samples taken at the time of organ retrieval may have prejudiced the latex test results [9].
• Collected data demonstrate that in the Veneto Region the efficiency of solid organ retrieval can be improved and that organ donor shortage may depend, beyond family refusal, on clinical and cultural factors that hamper stabilized heart-beating deaths [10].

Gene context of Tissue and Organ Harvesting

• There was, in addition, a difference in mean EGF levels from 'normal' bladder samples from non-tumour bearing areas of bladder in patients with bladder cancer compared with 'normal' bladder tissue obtained at the time of organ retrieval surgery [11].
• In conjunction with the organ harvesting procedure S100B levels increased, indicating that extracerebral sources of the protein also exist [12].
• Donor animals were treated with cobalt protoporphyrin (CoPP; 5 mg/kg IP) 24 hours prior to organ harvesting to induce HO-1 [13].
• All patients showed a pathologic TRH stimulation test prior to organ harvesting [14].
• Human lymphocyte antigen typing, therefore, could be performed locally before organ harvesting, making issues of donor heart preservation irrelevant [15].

References