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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
MeSH Review

Eye Injuries

 
 
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Disease relevance of Eye Injuries

  • The presence of an afferent pupillary defect or a nonreactive pupil was the most important factor in predicting the severity of eye injury (p = 0.0023), followed by facial fractures (p = 0.0084), and no eye opening or eye opening to pain within the Glasgow Coma Scale (p = 0.02) [1].
 

High impact information on Eye Injuries

  • In the accidents from the FAS data no difference was observed in the risk for eye injury between survivors in incidents involving airbag deployment and incidents not involving airbags [2].
  • From 1980 through 1986, acute perforating eye injury (ICD codes 871.0-871.9) was diagnosed in 345 residents of Allegheny County, Pennsylvania. The mean incidence rate was 3.49 per 100,000 person years [3].
  • Atracurium for open eye injuries [4].
  • The accidental release of methyl isocyanate gas in Bhopal, India, was reported to cause temporary blindness and other eye injuries in many of the exposed people [5].
  • However, in eye diseases or when eye injuries occur, GFAP is expressed in large quantities in retinal Müller cells [6].
 

Chemical compound and disease context of Eye Injuries

 

Biological context of Eye Injuries

  • METHODS: Retrospective analysis of 95 cases (103 eyes) of eye injuries in children younger than 17 years of age admitted to the Department of Ophthalmology, University Hospital of Patras, Greece, during a five-year period [12].
  • Intraocular concentrations of systemically administered gentamicin and cefazolin in eyes after a standard penetrating ocular injury were measured to determine the effect of eye injury on ocular pharmacokinetics [13].
  • Using data compiled from the ophthalmic literature and WHO's Blindness Data Bank, the available information on eye injuries from an epidemiological and public health perspective has been extensively reviewed [14].
 

Anatomical context of Eye Injuries

  • Based on the findings obtained in this study (xanthine oxidoreductase/xanthine oxidase activities are present in normal human corneas), we hypothesize that during various pathological states, xanthine oxidase-generated ROS might be involved in oxidative eye injury [15].
 

Gene context of Eye Injuries

  • Sport eye injuries referred to the Eye, Ear and Throat Hospital in Cork during the same period amounted to 107, of which 26 occurred in hurling [16].
  • The frequency of catastrophic eye injuries has been significantly reduced with the world-wide mandation of full facial protection for all Minor hockey players [17].
  • Only strabismus, with 676 (38.9%) admissions, accounted for more pediatric hospitalizations for eye injuries [18].
 

Analytical, diagnostic and therapeutic context of Eye Injuries

References

  1. Predictors of blinding or serious eye injury in blunt trauma. Joseph, E., Zak, R., Smith, S., Best, W.R., Gamelli, R.L., Dries, D.J. The Journal of trauma. (1992) [Pubmed]
  2. Do motor vehicle airbags increase risk of ocular injuries in adults? Lehto, K.S., Sulander, P.O., Tervo, T.M. Ophthalmology (2003) [Pubmed]
  3. Perforating eye injury in Allegheny County, Pennsylvania. Landen, D., Baker, D., LaPorte, R., Thoft, R.A. American journal of public health. (1990) [Pubmed]
  4. Atracurium for open eye injuries. Warner, D.O. Anesthesiology (1987) [Pubmed]
  5. Effect of methyl isocyanate (MIC) gas on the eyes of Fischer 344 rats. Gupta, B.N., Stefanski, S.A., Bucher, J.R., Hall, L.B. Environ. Health Perspect. (1987) [Pubmed]
  6. Expression of glial fibrillary acidic protein in primary cultures of human Müller cells. Lupien, C., Brenner, M., Guérin, S.L., Salesse, C. Exp. Eye Res. (2004) [Pubmed]
  7. Use of rocuronium in a pregnant patient with an open eye injury, receiving magnesium medication, for preterm labour. Gaiser, R.R., Seem, E.H. British journal of anaesthesia. (1996) [Pubmed]
  8. EMLA cream-induced eye injury. McKinlay, J.R., Hofmeister, E., Ross, E.V., MacAllister, W. Archives of dermatology. (1999) [Pubmed]
  9. The role of calcium gluconate in the treatment of hydrofluoric acid eye burn. Bentur, Y., Tannenbaum, S., Yaffe, Y., Halpert, M. Annals of emergency medicine. (1993) [Pubmed]
  10. Anhydrous ammonia eye injuries associated with illicit methamphetamine production. Lee, J.H., Farley, C.L., Brodrick, C.D., Blomquist, P.H. Annals of emergency medicine. (2003) [Pubmed]
  11. Effect of rocuronium compared with succinylcholine on intraocular pressure during rapid sequence induction of anaesthesia. Chiu, C.L., Jaais, F., Wang, C.Y. British journal of anaesthesia. (1999) [Pubmed]
  12. Severe ocular injuries in Greek children. Mela, E.K., Georgakopoulos, C.D., Georgalis, A., Koliopoulos, J.X., Gartaganis, S.P. Ophthalmic epidemiology. (2003) [Pubmed]
  13. Systemic antibiotic prophylaxis in penetrating ocular injuries. An experimental study. Alfaro, D.V., Pince, K., Park, J., Runyan, T., Ryan, S.J., Liggett, P.E. Retina (Philadelphia, Pa.) (1992) [Pubmed]
  14. The global impact of eye injuries. Négrel, A.D., Thylefors, B. Ophthalmic epidemiology. (1998) [Pubmed]
  15. Xanthine oxidoreductase and xanthine oxidase in human cornea. Cejková, J., Ardan, T., Filipec, M., Midelfart, A. Histol. Histopathol. (2002) [Pubmed]
  16. Analysis of hurling and camogie injuries. Crowley, P.J., Condon, K.C. British journal of sports medicine. (1989) [Pubmed]
  17. Ice hockey injuries. Benson, B.W., Meeuwisse, W.H. Medicine and sport science. (2005) [Pubmed]
  18. A survey of severe eye injuries in children. DeRespinis, P.A., Caputo, A.R., Fiore, P.M., Wagner, R.S. Am. J. Dis. Child. (1989) [Pubmed]
  19. Intraocular pressure changes in response to endotracheal intubation facilitated by atracurium or succinylcholine with or without lidocaine. Abdulla, W.Y., Flaifil, H.A. Acta anaesthesiologica Belgica. (1992) [Pubmed]
 
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