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MeSH Review:

Abnormalities, Drug-Induced

Farese, R.V. et al., Lewis, D.P. et al.

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Disease relevance of Abnormalities, Drug-Induced

Search terms included phenytoin, carbamazepine, phenobarbital, primidone, valproic acid, oral contraceptives, clomiphene, drug-induced abnormalities, spina bifida, anencephaly, neural tube defect, folate, folic acid, and folic acid deficiency [1].

High impact information on Abnormalities, Drug-Induced

The apparently normal stimulation of PGA and PGE in subjects with diabetic HH suggests that this syndrome is not associated with abnormal prostaglandin metabolism, despite the fact that drug-induced abnormalities of the latter may precipitate or aggravate the clinical syndrome in susceptible individuals [2].

References

Drug and environmental factors associated with adverse pregnancy outcomes. Part I: Antiepileptic drugs, contraceptives, smoking, and folate. Lewis, D.P., Van Dyke, D.C., Stumbo, P.J., Berg, M.J. The Annals of pharmacotherapy. (1998) [Pubmed]
Urinary prostaglandins following frusemide treatment and salt depletion in normal subjects and subjects with diabetic hyporeninaemic hypoaldosteronism. Farese, R.V., Rodriguez-Colomé, M., O'Malley, B.C. Clin. Endocrinol. (Oxf) (1980) [Pubmed]

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