Disease relevance of Vulvitis

• Squamous cell carcinoma arising in a case of vulvitis granulomatosa or vulval variant of Melkersson-Rosenthal syndrome [1].
• Neither thymidine-kinase activity, replication in macrophages, fusion activity of strains nor presence or absence of the Hpa I P-fragment were shown to be of importance for severity of vaginitis/vulvitis [2].
• The effectivity of two topical steroids, Apulein cream and Hydrocortisone ointment, was compared in women suffering from vulvitis and other superficial inflammations [3].
• RESULTS: Bacterial and fungal vulvitis, dermatitis, inflammatory dermatoses, secondary drug reactions, viral infections and a variety of vulvar tumors can all present as primary vulvar problems in prepubertal girls [4].
• CONCLUSION: Hypersensitivity to estrogen appears to be implicated in chronic, cyclic vulvitis and vulvitis related to HRT in these patients [5].

High impact information on Vulvitis

• CONCLUSIONS--Genital ulcers and vulvitis occurred with increased frequency in nonoxynol 9 sponge users [6].
• Etretinate: therapy for plasma cell vulvitis [7].
• A case of vulvitis granulomatosa or the vulval variant of Melkersson-Rosenthal syndrome (MRS) in a young adult patient with systemic lupus erythematosus is presented [1].
• Two patients exposed to 5-FU experienced chemical vulvitis [8].
• However, we have recently seen two women with symptoms suggesting the presence of condylomatous vulvitis where the use of 5% acetic acid for 10-15 min. was necessary for aceto-white lesions to develop [9].

Chemical compound and disease context of Vulvitis

• OBJECTIVE: To present the first reported case series of plasma cell vulvitis successfully treated with topical misoprostol [10].
• Of the nine patients with cyclic vulvitis, one recovered at menopause, and three responded to therapy aimed at lowering endogenous estrogen levels [5].
• Successful treatment of Zoon's vulvitis with high potency topical steroid [11].
• Herein we report a successful treatment with tranilast of an adult female patient with vulvitis granulomatosa [12].
• A 63-year-old woman with Zoon's vulvitis diagnosed on histopathology was treated with clobetasol propionate 0.05% [11].

Gene context of Vulvitis

• Proliferative, papillary vulvitis was identified in 16 of 34 (47%) free-ranging and captive female Florida panthers (Puma concolor coryi) monitored over a period from 1983-98 [13].

References