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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
MeSH Review

Sex Chromosomes

 
 
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Disease relevance of Sex Chromosomes

 

High impact information on Sex Chromosomes

  • We also report the results of a project at the MRC UK Mouse Genome Centre targeted at chromosome X. The project produced a YAC-based map containing 619 loci (with 121 loci in common with the Whitehead map and 498 additional loci), providing especially dense coverage of this sex chromosome [6].
  • A major locus involved in linear growth has been implicated within the pseudoautosomal region (PAR1) of the human sex chromosomes [7].
  • We have analysed the molecular evolution of the gene CHD, which is present on the Z and W sex chromosomes of birds [8].
  • These results challenge prevailing views of sex chromosome evolution, suggesting that acquisition of autosomal fertility genes is an important process in Y chromosome evolution [9].
  • Our data provide molecular evidence for a major divergence near the pseudoautosomal region, consistent with the hypothesis that hybrid sterility in these species results from abnormal pairing of sex chromosomes during male meiosis [10].
 

Chemical compound and disease context of Sex Chromosomes

 

Biological context of Sex Chromosomes

 

Anatomical context of Sex Chromosomes

 

Associations of Sex Chromosomes with chemical compounds

 

Gene context of Sex Chromosomes

 

Analytical, diagnostic and therapeutic context of Sex Chromosomes

References

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