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MeSH Review:

Granuloma Inguinale

Gupta, S. et al., Merianos, A. et al., Garg, B.R. et al., Birthistle, K. et al., Ahmed, B.A. et al., et al.

Gupta, Ajith, Kanwar, Sehgal, Kumar, Mete,

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High impact information on Granuloma Inguinale

Diagnostic polymerase chain reaction for donovanosis [1].
Azithromycin for the treatment of donovanosis [2].
Failure of trimethoprim in the treatment of donovanosis [3].
Successful treatment of donovanosis with ciprofloxacin [4].
Ceftriaxone in the treatment of chronic donovanosis in central Australia [5].

Chemical compound and disease context of Granuloma Inguinale

Efficacy of co-trimoxazole in Donovanosis. A preliminary report [6].
Treatment of donovanosis with norfloxacin [7].

Biological context of Granuloma Inguinale

Laboratory investigations like microscopy of tissue smear and nucleic acid amplification test for donovanosis, and serology and polymerase chain reaction for LGV may help in the diagnosis, but in endemic areas, in the absence of laboratory facilities, diagnosis largely depends on clinical characteristics [8].
The pharmacokinetics and safety profile of ceftriaxone make it a useful and cost-effective agent in the ambulatory management of donovanosis, especially in remote communities [5].

References

Diagnostic polymerase chain reaction for donovanosis. Carter, J., Bowden, F.J., Sriprakash, K.S., Bastian, I., Kemp, D.J. Clin. Infect. Dis. (1999) [Pubmed]
Azithromycin for the treatment of donovanosis. Bowden, F.J., Savage, J. Sexually transmitted infections. (1998) [Pubmed]
Failure of trimethoprim in the treatment of donovanosis. Birthistle, K., Greig, J., Hay, P. Genitourinary medicine. (1997) [Pubmed]
Successful treatment of donovanosis with ciprofloxacin. Ahmed, B.A., Tang, A. Genitourinary medicine. (1996) [Pubmed]
Ceftriaxone in the treatment of chronic donovanosis in central Australia. Merianos, A., Gilles, M., Chuah, J. Genitourinary medicine. (1994) [Pubmed]
Efficacy of co-trimoxazole in Donovanosis. A preliminary report. Garg, B.R., Lal, S., Sivamani, S. The British journal of venereal diseases. (1978) [Pubmed]
Treatment of donovanosis with norfloxacin. Ramanan, C., Sarma, P.S., Ghorpade, A., Das, M. International journal of dermatology. (1990) [Pubmed]
Genital elephantiasis and sexually transmitted infections - revisited. Gupta, S., Ajith, C., Kanwar, A.J., Sehgal, V.N., Kumar, B., Mete, U. International journal of STD & AIDS. (2006) [Pubmed]

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