High impact information on Retina

• This space contains two chondroitin sulfate proteoglycans, designated IPM 150 and IPM 200, which are likely to effect retinal adhesion and photoreceptor survival [1].
• Experiments in RPE-choroid preparations suggested that the choroidal effect of melatonin was independent of the neural retina, while the retinal effect was more complex and probably included a neural retinal component [2].
• Timolol is widely used in glaucoma treatment without sufficient knowledge of its vascular retinal effects [3].
• BACKGROUND: Although intravitreal ganciclovir dosages up to 500 microg have been demonstrated to be safe in some studies, other studies have shown toxic retinal effects in rabbit eyes without silicone oil at lower dosages [4].
• These findings suggest further effects of the drug than those mediated by GABA receptors, and support the contention that the cause of the field loss may be at least in part due to retinal effects [5].

Associations of Retina with chemical compounds

• This technology has recently been applied to the study of the retinal effects of parenteral magnesium sulphate [6].
• Delay of cardiac and retinal effects of digoxin following a rapidly attained serum concentration plateau [7].
• Our results support the concept that concentrations of 200 micrograms/0.1 mL of trifluridine, 400 micrograms/0.1 mL of hydroxyacyclovir, 200 micrograms/0.1 mL of acyclovir and 30 micrograms/0.1 mL of vidarabine can be combined for intravitreal injection without toxic retinal effects [8].

References