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MeSH Review

Occupational Diseases

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Disease relevance of Occupational Diseases


High impact information on Occupational Diseases

  • This article provides a sequence of steps that can be used by the practicing physician for detecting occupational diseases: Step 1: Routine screening questions for all patients (List of job titles? Exposure to fumes, dusts, chemicals, loud noise, or radiation? Temporal relationship of the chief complaint to activities at work or at home?) [5].
  • The predominant occupational disease attributed to diisocyanates, including MDI, is asthma; however, the potential for genotoxicity has also been of concern [6].
  • Norwegian physicians are obliged to report occupational diseases to the Labor Inspection Authority [7].
  • Renal cell cancer has been observed as an occupational disease in cases of very high exposure to trichloroethylene having led to narcotic or prenarcotic symptoms [8].
  • Only atopy and exposure level have consistently been reported as determinants of this occupational disease [9].

Chemical compound and disease context of Occupational Diseases


Gene context of Occupational Diseases

  • The large SDS, though dated, provides a tentative national look at the broad spectrum of occupational diseases as defined by WC and the occupations associated with those diseases in 1985 and 1986 [15].
  • Community health symposium. Part III: occupational disease and urban enviornment [16].
  • Vitiligo as an occupational disease [17].
  • The second indicator is the number of pre-employment medical examinations needed to reduce the number of new cases of an occupational disease by one (number needed to test, NNT) [18].
  • Their names were collected from the files of one biochemical laboratory performing urinary trichloroacetic acid determinations and from the Occupational Disease Register of Finland. Both the total mortality (SMR 69) and the cancer mortality (SMR 77) were lower than expected [19].


  1. Chronic diffuse interstitial fibrosis of the lung in uranium miners. Archer, V.E., Renzetti, A.D., Doggett, R.S., Jarvis, J.Q., Colby, T.V. J. Occup. Environ. Med. (1998) [Pubmed]
  2. Contemporary work-related environmental diseases. Trieff, N.M., Corrigan, G.E. Tex. Rep. Biol. Med. (1975) [Pubmed]
  3. A farmer's occupational airborne contact dermatitis masqueraded by coexisting rosacea: delayed diagnosis and legal acknowledgement. Spiewak, R., Dutkiewicz, J. Annals of agricultural and environmental medicine : AAEM. (2004) [Pubmed]
  4. Hypersensitivity pneumonitis: a comprehensive review. Wild, L.G., Lopez, M. Journal of investigational allergology & clinical immunology : official organ of the International Association of Asthmology (INTERASMA) and Sociedad Latinoamericana de Alergia e Inmunología. (2001) [Pubmed]
  5. The occupational and environmental health history. Goldman, R.H., Peters, J.M. JAMA (1981) [Pubmed]
  6. Induction of micronuclei following exposure to methylene di-phenyl diisocyanate: potential genotoxic metabolites. Zhong, B.Z., Siegel, P.D. Toxicol. Sci. (2000) [Pubmed]
  7. Notified cases of occupational asthma in Norway: exposure and consequences for health and income. Leira, H.L., Bratt, U., Slåstad, S. Am. J. Ind. Med. (2005) [Pubmed]
  8. Occupational exposure and urological cancer. Golka, K., Wiese, A., Assennato, G., Bolt, H.M. World journal of urology. (2004) [Pubmed]
  9. Occupational respiratory allergy in bakery workers: a review of the literature. Houba, R., Doekes, G., Heederik, D. Am. J. Ind. Med. (1998) [Pubmed]
  10. Are textile formaldehyde regulations reasonable? Experiences from the Finnish textile and clothing industries. Priha, E. Regulatory toxicology and pharmacology : RTP. (1995) [Pubmed]
  11. Occupational skin and respiratory diseases among hairdressers. Leino, T., Tammilehto, L., Hytönen, M., Sala, E., Paakkulainen, H., Kanerva, L. Scandinavian journal of work, environment & health. (1998) [Pubmed]
  12. Classical syndromes in occupational medicine: Phosphorus necrosis--a classical occupational disease. Felton, J.S. Am. J. Ind. Med. (1982) [Pubmed]
  13. Effectiveness of a nationwide interdisciplinary preventive programme for latex allergy. Latza, U., Haamann, F., Baur, X. International archives of occupational and environmental health. (2005) [Pubmed]
  14. Host factors in occupational diisocyanate asthma: a Swiss longitudinal study. Berode, M., Jost, M., Ruegger, M., Savolainen, H. International archives of occupational and environmental health. (2005) [Pubmed]
  15. Job-related diseases and occupations within a large workers' compensation data set. Leigh, J.P., Miller, T.R. Am. J. Ind. Med. (1998) [Pubmed]
  16. Community health symposium. Part III: occupational disease and urban enviornment. Woods, D. Canadian Medical Association journal. (1976) [Pubmed]
  17. Vitiligo as an occupational disease. Swarbrick, P. Occupational health; a journal for occupational health nurses. (1980) [Pubmed]
  18. Evaluation of the effectiveness of pre-employment screening. Sorgdrager, B., Hulshof, C.T., van Dijk, F.J. International archives of occupational and environmental health. (2004) [Pubmed]
  19. A cohort study on workers exposed to trichloroethylene. Tola, S., Vilhunen, R., Järvinen, E., Korkala, M.L. Journal of occupational medicine. : official publication of the Industrial Medical Association. (1980) [Pubmed]
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