Disease relevance of Occupational Diseases

• Many uranium miners have been disabled by and died of pulmonary fibrosis that was not recognized as an occupational disease [1].
• The particular occupational diseases discussed in detail are the clinical pneumoconioses, and the contemporary diseases: angiosarcoma from exposure to vinyl chloride and respiratory carcinoma from bichloromethyl ether exposure [2].
• Also presented are the problems with obtaining acceptance from the State Sanitary Authority for qualification of this case as an occupational disease, which was due to the coexistence of the non-occupational rosacea [3].
• In the United States, it has predominantly been considered an occupational disease, such as in farmer's lung, bagassosis, and in the plastics and paint industry with isocyanate exposure [4].

High impact information on Occupational Diseases

• This article provides a sequence of steps that can be used by the practicing physician for detecting occupational diseases: Step 1: Routine screening questions for all patients (List of job titles? Exposure to fumes, dusts, chemicals, loud noise, or radiation? Temporal relationship of the chief complaint to activities at work or at home?) [5].
• The predominant occupational disease attributed to diisocyanates, including MDI, is asthma; however, the potential for genotoxicity has also been of concern [6].
• Norwegian physicians are obliged to report occupational diseases to the Labor Inspection Authority [7].
• Renal cell cancer has been observed as an occupational disease in cases of very high exposure to trichloroethylene having led to narcotic or prenarcotic symptoms [8].
• Only atopy and exposure level have consistently been reported as determinants of this occupational disease [9].

Chemical compound and disease context of Occupational Diseases

• The comprehensive registration system of occupational diseases in Finland has enabled the study of the incidence of occupational diseases caused by formaldehyde among workers in the textile and clothing industries [10].
• Often a specific cause (eg, ammonium persulfate) can be found if occupational diseases are suspected and diagnosed [11].
• Classical syndromes in occupational medicine: Phosphorus necrosis--a classical occupational disease [12].
• This effective programme can be regarded as a model for the reduction of other occupational diseases such as bakers' or isocyanate asthma [13].
• Finally, those with an occupational disease were subjected to the methacholine provocation test [14].

Gene context of Occupational Diseases

• The large SDS, though dated, provides a tentative national look at the broad spectrum of occupational diseases as defined by WC and the occupations associated with those diseases in 1985 and 1986 [15].
• Community health symposium. Part III: occupational disease and urban enviornment [16].
• Vitiligo as an occupational disease [17].
• The second indicator is the number of pre-employment medical examinations needed to reduce the number of new cases of an occupational disease by one (number needed to test, NNT) [18].
• Their names were collected from the files of one biochemical laboratory performing urinary trichloroacetic acid determinations and from the Occupational Disease Register of Finland. Both the total mortality (SMR 69) and the cancer mortality (SMR 77) were lower than expected [19].

References