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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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SPA1, a WD-repeat protein specific to phytochrome A signal transduction.

The five members of the phytochrome photoreceptor family of Arabidopsis thaliana control morphogenesis differentially in response to light. Genetic analysis has identified a signaling pathway that is specifically activated by phytochrome A. A component in this pathway, SPA1 (for "suppressor of phyA-105"), functions in repression of photomorphogenesis and is required for normal photosensory specificity of phytochrome A. Molecular cloning of the SPA1 gene indicates that SPA1 is a WD (tryptophan-aspartic acid)-repeat protein that also shares sequence similarity with protein kinases. SPA1 can localize to the nucleus, suggesting a possible function in phytochrome A-specific regulation of gene expression.[1]

References

  1. SPA1, a WD-repeat protein specific to phytochrome A signal transduction. Hoecker, U., Tepperman, J.M., Quail, P.H. Science (1999) [Pubmed]
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