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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Oral administration of hot water extracts of Chlorella vulgaris reduces IgE production against milk casein in mice.

Hot water extract of Chlorella vulgaris (CVE) is a biological response modifier (BRM) which enhances resistance to Listeria monocytogenes through augmentation of helper T cell type 1 (Thl) responses producing gamma-interferon (gammaIFN). We show here that oral administration of CVE in mice suppressed the production of immunoglobulin (Ig)E against casein antigen accompanied by increased gammaIFN and IL-12 mRNA expression. Oral administration of CVE enhanced Thl response to casein in the spleen of casein immunized mice. CVE may be useful for prevention of allergic diseases with a predominant Th2 response.[1]

References

  1. Oral administration of hot water extracts of Chlorella vulgaris reduces IgE production against milk casein in mice. Hasegawa, T., Ito, K., Ueno, S., Kumamoto, S., Ando, Y., Yamada, A., Nomoto, K., Yasunobu, Y. Int. J. Immunopharmacol. (1999) [Pubmed]
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