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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Septins: cytoskeletal polymers or signalling GTPases?

Septins are a family of conserved proteins that have been implicated in a variety of cellular functions involving specialized regions of the cell cortex and changes in cell shape. The biochemistry and localization of septins suggest that they form a novel cytoskeletal system or that they function as scaffolds for the assembly of signalling complexes. This article discusses septin biochemistry and septin-interacting proteins, focusing on the missing link between the structure and biochemical properties of septin proteins, and on how they function at a molecular level in processes such as cytokinesis and yeast budding.[1]

References

  1. Septins: cytoskeletal polymers or signalling GTPases? Field, C.M., Kellogg, D. Trends Cell Biol. (1999) [Pubmed]
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