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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 

Regulating the activity of a cardioacceleratory peptide.

We measured the effect of crustacean cardioactive peptide on Drosophila heart rate in the animal and in a tissue preparation. Crustacean cardioactive peptide increased in vivo basal heart rate 1%, 6%, and 19% and increased in vitro basal heart rate 52%, 25%, and 35% in larvae, pupae, and adults, respectively. In the tissue preparation, the acceleratory period was followed by decreased in vitro heart rates of 42%, 16%, and 13% in larvae, pupae, and adults, respectively. The effects observed in the animal and tissue and in larvae, pupae, and adults suggest that Drosophila crustacean cardioactive peptide cardiac signaling is modulated and developmentally regulated.[1]

References

  1. Regulating the activity of a cardioacceleratory peptide. Nichols, R., Kaminski, S., Walling, E., Zornik, E. Peptides (1999) [Pubmed]
 
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