The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound

Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

[search][options]

Editor

Personal info

View

About

Terms

Javascript disabled

Please enable Javascript support in your browser to use this application.

Instructions on how to enable JavaScript on different browsers can be found here: http://www.google.com/support/bin/answer.py?answer=23852.

[edit this page]

Daoud, A.A. et al.

The effect of antioxidant preparation (antox) on the course and efficacy of treatment of trichinosis.

This study evaluated the effect of administration of exogenous antioxidant (antox) on the course and treatment of Trichinella spiralis in the intestinal phase (2 days post infection, p.i.) and the muscle phase (35 days p.i.) using albino rats as an experimental model. The results indicated that the administration of antox had led to delayed expulsion of adult worms from the small intestine, decreased inflammatory reactions in the intestines and muscles and causing an increase in the muscle larval burden. The intake of antioxidant decreased the efficacy of mebendazole on adult worms in the intestinai phase, while it enhanced the effect of treatment in the muscle phase and the number of larvae was highly decreased. So, antox inhibited free radical generation in small intestine which acts as a contributing factor to the rejection process. But, in muscle phase, the decreased inflammatory reaction around larvae increases the chance of the drug to reach larvae and affects them.[1]

References

The effect of antioxidant preparation (antox) on the course and efficacy of treatment of trichinosis. Daoud, A.A., Abdel-Ghaffar, A.E., Deyab, F.A., Essa, T.M. Journal of the Egyptian Society of Parasitology. (2000) [Pubmed]

Annotations and hyperlinks in this abstract are from individual authors of WikiGenes or automatically generated by the WikiGenes Data Mining Engine. The abstract is from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg