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Boiko, S.S. et al.

Pharmacokinetics of new nootropic acylprolyldipeptide and its penetration across the blood-brain barrier after oral administration.

Pharmacokinetics of GVS-111, a new acylprolyldipeptide with nootropic properties and its penetration across the blood-brain barrier were studied in rats using HPLC. It was found that the dipeptide is absorbed in the gastrointestinal tract, enters the circulation, and penetrates through the blood-brain barrier in an unmodified state.[1]

References

Pharmacokinetics of new nootropic acylprolyldipeptide and its penetration across the blood-brain barrier after oral administration. Boiko, S.S., Ostrovskaya, R.U., Zherdev, V.P., Korotkov, S.A., Gudasheva, T.A., Voronina, T.A., Seredenin, S.B. Bull. Exp. Biol. Med. (2000) [Pubmed]

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