The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Metabolic activation of 3-methylcholanthrene in mouse skin: fluorescence spectral evidence indicates the involvement of diol-epoxides formed in the 7,8,9,10-ring.

Hydrolysates of DNA that had been isolated from mouse skin treated with 3H-labelled 3-methylcholanthrene were subjected to chromatography on Sephadex LH20 columns and 3H-labelled products that eluted in the region expected for nucleoside-hydrocarbon adducts were purified further by high pressure liquid chromatography; eight major and one minor products were resolved and their fluorescence spectra were determined using photon-counting spectrophotofluorimetry. The fluorescence spectra of six of the major products are anthracene-like and are similar to the previously-reported spectrum of 7,8,9,10-tetrahydro-3-methylcholanthrene, a result that is consistent with metabolic activation involving diol-epoxide formation in the 7,8,9,10-ring of 3-methylcholanthrene. The fluorescence spectra of the other two major products are also anthracene-like, but their maxima are shifted to longer wavelengths relative to the maxima in the spectrum of 7,8,9,10-tetrahydro-3-methylcholanthrene. The minor product possesses a fluorescence spectrum that is not anthracene-like and that is dissimilar from the spectra of products formed from 3-methylcholanthrene 11,12-oxide.[1]


WikiGenes - Universities