- Lethal outcome of a patient with a complete dihydropyrimidine dehydrogenase (DPD) deficiency after administration of 5-fluorouracil: frequency of the common IVS14+1G>A mutation causing DPD deficiency. van Kuilenburg, A.B., Muller, E.W., Haasjes, J., Meinsma, R., Zoetekouw, L., Waterham, H.R., Baas, F., Richel, D.J., van Gennip, A.H. Clin. Cancer Res. (2001)